Results 171 to 180 of about 90,675 (307)

Microarray analysis of tamoxifen resistance in breast cancer.

, 2009
PhDTamoxifen remains a widely used hormone therapy for pre and postmenopausal women with hormone receptor positive breast cancer in both adjuvant and metastatic disease settings. Resistance to this well tolerated and cost-effective drug limits its use.
Moss, Charlotte
core  

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Association between estrogen receptor alpha 36 expression and the risk of deep infiltrating endometriosis. [PDF]

Front Endocrinol (Lausanne)
Zhang Y, Yu T, Zhao C, Xue R.
europepmc   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Lack of endothelial estrogen receptor alpha signaling exacerbates abdominal aortic aneurysm in male mice. [PDF]

Am J Physiol Heart Circ Physiol
Sharma N, Huang Y, Jia G, Martinez-Lemus LA, Padilla J, Manrique-Acevedo C.   +5 more
europepmc   +1 more source

Estrogen receptor alpha polymorphism is associated with pelvic organ prolapse risk

, 2010
[[abstract]]Estrogen and estrogen receptors are known to play important roles in the pathophysiology of pelvic organ prolapse (POP). We investigated whether estrogen receptor alpha (ER alpha) gene polymorphisms were associated with POP risk by conducting
Chen, HY (Chen, Huey-Yi); Chung, YW (Chung, Ya-Wen); Lin, WY (Lin, Wei-Yong); Chen, WC (Chen, Wei-Chi); Tsai, FJ (Tsai, Fuu-Jen); Tsai, CH (Tsai, Chang-Hai)
core  

Cognition in menopausal women

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Cognitive health in postmenopausal women is significantly affected by hormonal shifts, especially the drop in estrogen levels. This review explores the intricate relationship between menopause and cognitive functions across six domains: perception, attention, memory, language, executive functioning, and motor skills.
Suvarna Khadilkar, Jharna Mahajan (Bhanushali), Anuradha P. Mahto, Satish Khadilkar   +3 more
wiley   +1 more source

Transcriptional Activation of Estrogen Receptor-Alpha and Estrogen Receptor-Beta from Elephant Shark (<i>Callorhynchus milii</i>). [PDF]

Genes (Basel)
Ao Y, Narita H, Takagi W, Hyodo S, Baker ME, Katsu Y.   +5 more
europepmc   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

Study of Estrogen Receptor Alpha Gene Polymorphisms (<i>ERα</i>, <i>ESR1</i>) in Women with Ovarian Cancer. [PDF]

Int J Mol Sci
Łukasiewicz H, Samulak D, Romanowicz H, Smolarz B.   +3 more
europepmc   +1 more source