Results 281 to 290 of about 90,675 (307)

Binding studies on estrogen receptor alpha

2009
Die wachsende Anzahl an charakterisierten molekularen Rezeptoren liefert die Basis für das struktur-basierte Design von aktiven Verbindungen zur Entwicklung eines neuen Medikamentes. Ausgehend von einer bekannten oder hypothetischen Wirkungsweise oder einem Bindungsmechanismus wird eine vernünftige Vorlage entworfen, die später experimentell getestet ...
openaire   +1 more source

α-Mangostin and its derivatives against estrogen receptor alpha

Journal of Biomolecular Structure and Dynamics, 2022
Richa Mardianingrum, Muhammad Yusuf, Maywan Hariono   +2 more
exaly  

Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex.

Cancer research, 2001
4-Hydroxytamoxifen (4-OHT), a selective estrogen receptor modulator, is an agonist at a transforming growth factor-alpha (TGF-alpha) target gene in situ in MDA-MB-231 human breast cancer cells stably transfected with wild-type human ERalpha. In contrast, raloxifene (Ral) is a complete antiestrogen silencing activation function (AF) 1 and AF2 in this ...
H, Liu, E S, Lee, A, Deb Los Reyes, J W, Zapf, V C, Jordan   +4 more
openaire   +1 more source

Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases

International Journal of Molecular Sciences, 2020
Madhulika Tripathi, Paul M Yen, Brijesh K Singh   +2 more
exaly  

Immunohistochemical examination of androgen receptor and estrogen receptor alpha expressions in obstructive and non-obstructive azoospermia

Systems Biology in Reproductive Medicine, 2021
Yurdun Kuyucu, Gulfidan Coşkun, Dilek Saker   +2 more
exaly  

Estrogen Receptor Alpha

2017
openaire   +1 more source

Neo-tanshinlactone selectively inhibits the proliferation of estrogen receptor positive breast cancer cells through transcriptional down-regulation of estrogen receptor alpha

Pharmacological Research, 2016
Wanjun Lin, Jiajun Huang, Xiaolin Liao   +2 more
exaly  

Negative feedback loop of BRCA1–BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1

International Journal of Biochemistry and Cell Biology, 2010
Irmgard Irminger-Finger
exaly  

Estrogen Receptor Alpha ESR1

2008
openaire   +1 more source

Preliminary Molecular Dynamic Simulations of the Estrogen Receptor Alpha Ligand Binding Domain from Antagonist to Apo

International Journal of Environmental Research and Public Health, 2008
Adrian E Roitberg
exaly