Results 191 to 200 of about 304,831 (358)

Analysis of ligand-dependent changes in estrogen receptor and thyroid hormone receptor mRNA and protein expression in the developing rat cerebellum [PDF]

open access: green, 2011
Attila Zsarnovszky   +8 more
openalex  

Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy

open access: gold, 2019
Peiye Song   +12 more
openalex   +1 more source

Estrogen receptor [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo   +6 more
wiley   +1 more source

Multicomplex Pharmacophore Modeling of Estrogen Receptors Suggests the Probable Repurposing of Procaterol as an Antiproliferative Agent Against Breast Cancer Cells. [PDF]

open access: yesInt J Mol Sci
Vazquez-Mendoza LH   +6 more
europepmc   +1 more source

The clinical and pathogenetic significance of estrogen receptor‐β expression in chronic liver diseases and liver carcinoma [PDF]

open access: bronze, 2003
Massimo Iavarone   +6 more
openalex   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Ovarian Cancer-Epidemiology, Classification, Pathogenesis, Treatment, and Estrogen Receptors' Molecular Backgrounds. [PDF]

open access: yesInt J Mol Sci
Smolarz B   +6 more
europepmc   +1 more source

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