Beyond Hot Flashes: The Role of Estrogen Receptors in Menopausal Mental Health and Cognitive Decline. [PDF]
Cho JM, Lee J, Ahn EM, Bae J.
europepmc +1 more source
Analysis of ligand-dependent changes in estrogen receptor and thyroid hormone receptor mRNA and protein expression in the developing rat cerebellum [PDF]
Attila Zsarnovszky +8 more
openalex
Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system [PDF]
Wendy S. Post
openalex +1 more source
Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo +6 more
wiley +1 more source
Multicomplex Pharmacophore Modeling of Estrogen Receptors Suggests the Probable Repurposing of Procaterol as an Antiproliferative Agent Against Breast Cancer Cells. [PDF]
Vazquez-Mendoza LH +6 more
europepmc +1 more source
The clinical and pathogenetic significance of estrogen receptor‐β expression in chronic liver diseases and liver carcinoma [PDF]
Massimo Iavarone +6 more
openalex +1 more source
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su +18 more
wiley +1 more source
Ovarian Cancer-Epidemiology, Classification, Pathogenesis, Treatment, and Estrogen Receptors' Molecular Backgrounds. [PDF]
Smolarz B +6 more
europepmc +1 more source

