Results 241 to 250 of about 2,557,731 (353)

Lack of correlation of a histochemical method for estrogen receptor analysis with the biochemical assay results [PDF]

, 1982
W. B. Panko, Carlos A. Mattioli, Thomas M. Wheeler   +2 more
openalex   +1 more source

Functionalized in Triplicate: A Ring‐By‐Ring Approach to Tailored Prodiginine Derivatives for Site‐Specific Conjugation Through Click Chemistry

Chemistry – A European Journal, EarlyView.
Prodigiosin is a potent cytotoxic alkaloid but lacks target selectivity. We advance functionalization of all three pyrrole rings of prodigiosin to enable site‐specific conjugation via click chemistry. The presented azide‐ and maleimide‐functionalized prodiginines are suitable for generating covalent prodiginine conjugates and attaching auspicious ...
T. Moritz Weber, Jörg Pietruszka
wiley   +1 more source

Antitumor Efficacy, Pharmacokinetics, and Toxicity Studies of Novel Estrogen Receptors Targeted PEGylated Liposomes Encapsulating Paclitaxel and Cisplatin in SKOV-3 Tumor-Bearing Nude Mice, ICR Mice, and SD Rats. [PDF]

Mol Pharm
Zhu M, Jia J, Tang H, Xie Y, Lv Z, Bao H, Zhang Y, Miao D, Guo X, Chen K, Wang S, Yu L, Pei J.   +12 more
europepmc   +1 more source

Interaction between zearalenone, an estrogenic mycotoxin, and the estrogen receptor of the rat brain

, 1982
Motoji Kitagawa, Fumio Tashiro, Yuji Ueno   +2 more
openalex   +2 more sources

Development of Carborane‐Based Halogenated Naphthyridinone‐Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands

ChemMedChem, EarlyView.
There is no suitable radioligand for positron emission tomography imaging of CB2R overexpression for routine clinical usage. Herein, the synthesis, characterization, binding affinity, and docking studies of carborane‐based halo‐substituted naphthyridinone derivatives as CB2R ligands are presented.
Lea Ueberham, Winnie Deuther‐Conrad, Peter Lönnecke, Aleksandr Kazimir, Evamarie Hey‐Hawkins   +4 more
wiley   +1 more source

Highly Sensitive, Low‐Cost Deep‐UV Resonant Raman Microspectroscopy Systems

Chemistry–Methods, EarlyView.
Low‐cost deep UV resonant Raman microscope for chemical sensing and imaging has been developed and its performance has been experimentally validated for several potential applications. Multimodal imaging capabilities of a new instrument have been demonstrated as well.
Joseph Harrington, Vsevolod Cheburkanov, Mykyta Kizilov, Ilya Kulagin, Georgi I. Petrov, Vladislav V. Yakovlev   +5 more
wiley   +1 more source

Evaluation of Grading Estrogen Receptors in Breast Cancer Using Fully Automated Rapid Immunohistochemistry Based on Alternating-Current Electric Field Technology. [PDF]

Cancers (Basel)
Kudo C, Terata K, Nanjo H, Nomura K, Hiroshima Y, Takahashi E, Yamaguchi A, Konno H, Onji M, Wakamatsu Y, Kimura Y, Takashima S, Wakita A, Sato Y, Minamiya Y, Imai K.   +15 more
europepmc   +1 more source

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano, Milko Massimiliano Radicioni, Gerhard Garhöfer, Martina Cartwright, Markus Müller, Iris Kopeloff, Luigi Moro, Nicholas Squittieri, Alessandro Mazzetti   +8 more
wiley   +1 more source

Interaction of Per- and Polyfluoroalkyl Substances with Estrogen Receptors in Rainbow Trout (Oncorhynchus mykiss): An In Silico Investigation. [PDF]

Environ Sci Technol
Bali SK, Hall K, Massoud RI, Almeida NMS, Wilson AK.   +4 more
europepmc   +1 more source

Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women

Cancer Communications, EarlyView.
Iris Garrido‐Cano, Marta Tapia, Juan Carbonell, Carlos Peña, Sandra Torres‐Ruiz, Anna Ágreda‐Roca, Ana Lameirinhas, Cristina Tebar, Octavio Burgués, Cristina Hernando, Ana Lluch, Fara Brasó‐Maristany, Aleix Prat, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo   +15 more
wiley   +1 more source