Results 271 to 280 of about 297,708 (362)

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

Evaluation of the Pathologic and Prognostic Correlates of Estrogen Receptors in Primary Breast Cancer

, 1982
James R. Skinner, Harold J. Wanebo, William L. Betsill, Morton C. Wilhelm, Charles R. Drake, Robert M. MacLeod   +5 more
openalex   +2 more sources

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

Arthritis &Rheumatology, EarlyView.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source

Estrogen Regulates Ca²⁺ to Promote Mitochondrial Function Through G-Protein-Coupled Estrogen Receptors During Oocyte Maturation. [PDF]

Biomolecules
Liu Q, Li J, Li Y, Cheng M, Zhang H, Ma B.   +5 more
europepmc   +1 more source

Associations of specific pesticides and incident rheumatoid arthritis among female spouses in the Agricultural Health Study

Arthritis &Rheumatology, Accepted Article.
Objectives Growing evidence suggests farming and agricultural pesticide use may be associated with rheumatoid arthritis (RA), but few studies have examined specific pesticides and RA among farm women, who may personally use pesticides or be indirectly exposed.
Christine G. Parks, Darya Leyzarovich, Ghassan B. Hamra, Karen H. Costenbader, Dazhe Chen, Jonathan N. Hofmann, Laura E. Beane Freeman, Dale P. Sandler   +7 more
wiley   +1 more source

Sex Differences in Auditory Brainstem Responses of Two Rat Models of Autism: Environmental and Genetic Contributions to Autism‐Like Auditory Function

Autism Research, EarlyView.
ABSTRACT Autism is an early‐onset neurodevelopmental disorder characterized by restricted, repetitive behaviors and atypical patterns of social communication and interaction. A considerable proportion of autistic individuals experience divergent auditory perception, which can interfere with their ability to navigate everyday sound environments ...
Sara Cacciato‐Salcedo, Ana B. Lao‐Rodríguez, Manuel S. Malmierca   +2 more
wiley   +1 more source

Interaction of Per- and Polyfluoroalkyl Substances with Estrogen Receptors in Rainbow Trout (Oncorhynchus mykiss): An In Silico Investigation. [PDF]

Environ Sci Technol
Bali SK, Hall K, Massoud RI, Almeida NMS, Wilson AK.   +4 more
europepmc   +1 more source

Real‐world treatment patterns among patients diagnosed with hormone receptor‐positive metastatic breast cancer in the USA

British Journal of Clinical Pharmacology, EarlyView.
Aims Clinical guidelines for breast cancer management have evolved in the past decade. However, limited evidence exists regarding uptake of novel drug classes in management of hormone receptor‐positive (HR+) metastatic breast cancer (MBC) in the USA and whether disparities exist by race and ethnicity.
Kexin Zhu, Coral O. Omene, Antoinette Stroup, Elisa V. Bandera, Farzin Khosrow‐Khavar   +4 more
wiley   +1 more source

Reproductive function and behaviors: an update on the role of neural estrogen receptors alpha and beta. [PDF]

Front Endocrinol (Lausanne)
Torres T, Adam N, Mhaouty-Kodja S, Naulé L.   +3 more
europepmc   +1 more source

Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang, Li Zhou, Jennifer A. Winton, Kyle T. Matschke, Constantino Kantaridis, Kristine Doyle, Kimberly C. Lee, Naihan Chen, Yuanyuan Zhang, Weiwei Tan   +9 more
wiley   +1 more source