Results 41 to 50 of about 784,665 (196)
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Nicole Berchtold +15 more
core +3 more sources
The Role of Estrogen Receptors in Urothelial Cancer
Frontiers in Endocrinology, 2021 Epidemiological data have indicated that there are some sex-related differences in bladder cancer. Indeed, the incidence of bladder cancer in men has been substantially higher than that in women throughout the world, while women tend to have higher stage
Takuro Goto +4 more
doaj +1 more source
A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen [PDF]
, 2012 SynthSys is a Centre for Integrative Systems Biology (CISB) funded by BBSRC and EPSRC, reference BB/D019621/1.Background: Estrogen receptors alpha (ER) are implicated in many types of female cancers, and are the common target for anti-cancer therapy ...
Harrison, David J +11 more
core +1 more source
The Iraqi Journal of Medical Sciences, 2009 Background: Estrogen hormone has been implicated in the pathogenesis of different genital tract pathologies and in counteracting the progress of normal pregnancy.
Nidhal Abdul-Mohaymen +2 more
doaj +1 more source
Single-cell states in the estrogen response of breast cancer cell lines [PDF]
, 2014 Estrogen responsive breast cancer cell lines have been extensively studied to characterize transcriptional patterns in hormone-responsive tumors. Nevertheless, due to current technological limitations, genome-wide studies have typically been limited to ...
Andrea Gamba +49 more
core +1 more source
Targeting mutant estrogen receptors
eLife, 2019 A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
Suzanne E Wardell +2 more
doaj +1 more source
Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]
, 2013 In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo +55 more
core +2 more sources
Estrogen and Progesterone Receptors in Human Colorectal Tumour Cells (Study of 70 Cases)
The International Journal of Biological Markers, 1988 Estrogen and progesterone receptors were studied in 70 cases of human colorectal cancer by a cytochemical technique. 28.5% of the cases were estrogen-receptor positive and 42.8% progesterone-receptor positive.
G. Bracali +5 more
doaj +1 more source
Local estrogen formation and its regulation in endometriosis
Reproductive Medicine and Biology, 2019 Background It has been well established that endometriosis is an estrogen‐dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen‐dependent growth and maintenance of the ectopic ...
Taisuke Mori +7 more
doaj +1 more source
, 2021 Impaired circulating estrogen levels have been related to impaired glycemic homeostasis and diabetes mellitus (DM), both in females and males. However, for the last twenty years, the relationship between estrogen, glycemic homeostasis and the mechanisms ...
Ubiratan Fabres Machado +2 more
core +1 more source