Results 41 to 50 of about 163,959 (310)
, 2023 Estrogen is an essential sex steroid hormone that functions primarily in female reproductive system, as well as in a variety of tissues and organs with pleiotropic effects, such as in cardiovascular, nervous, immune, and musculoskeletal systems.
Kuniko Horie +3 more
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Silibinin protects GLUTag cells from PA-induced injury via suppressing endoplasmic reticulum stress
CyTA - Journal of Food, 2023 Silibinin is a natural flavonoid with anti-diabetic activity. Glucagon-like peptide−1 (GLP−1), an intestinal hormone mainly secreted from L cells, which regulates insulin production and sensitivity, appears to be a potential therapeutic strategy for T2DM.
Xinyi Shi +9 more
doaj +1 more source
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Nicole Berchtold +15 more
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Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain
Molecular Imaging, 2008 Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell +3 more
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Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line
Research in Pharmaceutical Sciences, 2018 Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi +2 more
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Biology of Sex Differences, 2020 Estrogen plays substantial roles in pain modulation; however, studies concerning sex hormones and nociception often yield confusing results. The discrepancy could be a result of lack of consensus to regard estrogen as a variable when working with animal ...
Wenxin Zhang +10 more
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BMC Biology, 2022 Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the maintenance of ...
Yuping Zhou +13 more
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Epigenetics and the Estrogen Receptor
Annals of the New York Academy of Sciences, 2006 Abstract: The position effect variegation in Drosophila and Schizosaccharomyces pombe, and higher‐order chromatin structure regulation in yeast, is orchestrated by modifier genes of the Su(var) group, (e.g., histone deacetylases ([HDACs]), protein phosphatases) and enhancer E(Var) group (e.g., ATP [adenosine 5′‐triphosphate]‐dependent nucleosome ...
Leader, Jennifer E. +4 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Estrogen Receptors in the Male [PDF]
Archives of Andrology, 1981 Estrogens in the male are secreted by the testes and derived extragonadally from the aromatization of certain androgens. In some brain regions critical for the control of gonadotropin secretion and behavior, androgens may be aromatized to estrogens within the cells that are regulated. Estrogen may have other physiological roles on the testes to control
R B, Dickson, C R, Clark
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