Studies have shown that estrogen replacement therapy and estrogen plus progestin replacement therapy alter serum levels of total, LDL and HDL cholesterol levels.
N.C. Nogueira-de-Souza+6 more
doaj +1 more source
Shereshevsky-Turner syndrome: Estrogen replacement therapy and cardiovascular risk factors [PDF]
Aim. To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT ...
O A Yevstigneeva+5 more
doaj +1 more source
Malignancies Associated with Extraovarian Endometriosis: A Literature Review
Endometriosis-associated ovarian malignancies have been well documented. Although these malignancies also occur as extraovarian lesions, little is known about them. Thus, this literature review aimed to further explore these rarely experienced tumors.
Naoki Inoue+4 more
doaj +1 more source
Statistical adjustment for a measure of healthy lifestyle doesn't yield the truth about hormone therapy [PDF]
The Women's Health Initiative randomized clinical trial of hormone therapy found no benefit of hormones in preventive cardiovascular disease, a finding in striking contrast with a large body of observational research. Understanding whether better methodology and/or statistical adjustment might have prevented the erroneous conclusions of observational ...
arxiv +1 more source
Estrogen replacement therapy and cardioprotection: mechanisms and controversies
Epidemiological and case-controlled studies suggest that estrogen replacement therapy might be beneficial in terms of primary prevention of coronary heart disease (CHD).
M.T.R. Subbiah
doaj +1 more source
Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy
Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use.
Alexander L. Pan+3 more
doaj +1 more source
Targeting mutant estrogen receptors
A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
Suzanne E Wardell+2 more
doaj +1 more source
Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
OBJECTIVE: In this study, we aimed to determine the frequency of etiologic factors that causes postmenopausal bleeding. STUDY DESIGN: For the purpose, a total number of 200 women with postmenopausal bleeding were included in the study.
Umit Yasemin Sert+2 more
doaj +1 more source
Efficient algorithms for building representative matched pairs with enhanced generalizability [PDF]
Many recent efforts center on assessing the ability of real-world evidence (RWE) generated from non-randomized, observational data to produce results compatible with those from randomized controlled trials (RCTs). One noticeable endeavor is the RCT DUPLICATE initiative (Franklin et al., 2020, 2021).
arxiv
A mathematical model of Breast cancer (ER+) with excess estrogen: Mixed treatments using Ketogenic diet, endocrine therapy and Immunotherapy [PDF]
Breast Cancer is a major public health problem and the most common diagnosed malignancy in woman. There have been significant developments in clinical approaches and theoretical experimental to understand the interactions of cancer cells dynamics with the immune system, also developments on analytical and computational models to help provide insights ...
arxiv