Results 61 to 70 of about 95,231 (351)

Functional and molecular neuroimaging of menopause and hormone replacement therapy

open access: yesFrontiers in Neuroscience, 2014
The level of gonadal hormones to which the female brain is exposed considerably changes across the menopausal transition, which in turn, is likely to be of great relevance for neurodegenerative diseases and psychiatric disorders.
Erika eComasco   +3 more
doaj   +1 more source

A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9. [PDF]

open access: yesPLoS ONE, 2016
Poor outcome in response to hepatitis C virus, including higher viral load, hepatocellular carcinoma and cirrhosis, is more associated with men and postmenopausal women than with premenopausal women and women receiving hormone replacement therapy ...
Laura Ulitzky   +5 more
doaj   +1 more source

Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]

open access: yes, 2017
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele   +12 more
core   +2 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Histological Changes in the Fracture Callus Following the Administration of Water Extract of Piper Sarmentosum (Daun Kadok) in Estrogen-Deficient Rats [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Background: The fracture healing is impaired in osteoporosis. Piper sarmentosum is a plant, which contains potent antioxidant, naringenin that may enhance fracture healing. The present histological study aimed to determine the effects of water extract of
Mohamed Abdalla Estai   +5 more
doaj  

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

Poor Compliance to Hormone Therapy and Decreased Bone Mineral Density in Women with Premature Ovarian Insufficiency. [PDF]

open access: yesPLoS ONE, 2016
Premature ovarian insufficiency leads to through infertility and estrogen deficiency. Optimal management encompasses estrogen replacement therapy. Long-term outcome of women with POI is not known.
Anne Bachelot   +6 more
doaj   +1 more source

#370 : Hormone Replacement Therapy and Risk of Cardiovascular Diseases in Postmenopausal Women Aged 50-59 Years: A Systematic Review of Randomized Controlled Trials

open access: yesFertility & Reproduction, 2023
Background and Aims: Cardiovascular diseases are the leading cause of mortality worldwide. Due to declining estrogen levels, women are at higher risk of contracting cardiovascular diseases.
Reynardi Larope Sutanto   +2 more
doaj   +1 more source

Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis [PDF]

open access: yes, 2002
Hormone replacement therapy (HRT) increases the risk of venous thrombosis. We investigated whether this risk is affected by carriership of hereditary prothrombotic abnormalities.
A. Rumley   +26 more
core   +1 more source

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