Results 221 to 230 of about 12,973 (282)
The Indian journal of medical research, 1975 Some of the next articles are maybe not open access.
Related searches:
Related searches:
Early-estrogen syndrome in the rat by the non-steroidal estrogen diethylstilbestrol
Experientia, 1967Typisches, durch Ostrogene (fruhpostnatale Periode) bei weiblichen und mannlichen Ratten induziertes Syndrom, wird auch durch nicht-steroidales Ostrogen, das Diathylstilbostrol, ausgelost. Auffallend wellenformige Granulosazellenschicht in den grossen Graafschen Follikeln.
J, Presl +3 more
openaire +2 more sources
Developmental evaluation of a potential non-steroidal estrogen: triclosan
Marine Environmental Research, 2000Triclosan is an antibacterial agent commonly used in industry and often detected in waste-water effluent. The potential of triclosan to act as an endocrine disruptor was examined because its chemical structure closely resembles known non-steroidal estrogens (e.g. DES, bisphenol A).
C M, Foran, E R, Bennett, W H, Benson
openaire +2 more sources
Bioorganic & Medicinal Chemistry, 2003
Estrogens regulate many biological functions, often acting in a tissue-selective manner. Their tissue-selective action is believed to involve differential estrogen action through the two estrogen receptor (ER) subtypes, ERalpha and ERbeta, as well as differential interaction of the ligand-receptor complexes with promoters and coregulator proteins.
Usha, Ghosh +6 more
openaire +2 more sources
Estrogens regulate many biological functions, often acting in a tissue-selective manner. Their tissue-selective action is believed to involve differential estrogen action through the two estrogen receptor (ER) subtypes, ERalpha and ERbeta, as well as differential interaction of the ligand-receptor complexes with promoters and coregulator proteins.
Usha, Ghosh +6 more
openaire +2 more sources
Current Computer-Aided Drug Design, 2023
Background:Breast cancer is one of the most commonly diagnosed cancer types among women worldwide. Cytochrome P450 aromatase (CYP19A1) is an enzyme in vertebrates that selectively catalyzes the biosynthesis of estrogens from androgenic precursors. Researchers have increasingly focused on developing non-steroidal aromatase inhibitors (NSAIs) for their ...
Khushboo Pandey +5 more
openaire +2 more sources
Background:Breast cancer is one of the most commonly diagnosed cancer types among women worldwide. Cytochrome P450 aromatase (CYP19A1) is an enzyme in vertebrates that selectively catalyzes the biosynthesis of estrogens from androgenic precursors. Researchers have increasingly focused on developing non-steroidal aromatase inhibitors (NSAIs) for their ...
Khushboo Pandey +5 more
openaire +2 more sources
The Journal of Steroid Biochemistry and Molecular Biology, 1997
Estrogen receptor (ER), a member of the nuclear receptor superfamily, exerts prominent physiological roles in both humans and other species by acting directly as a transcription factor, altering nuclear gene expression. One peculiarity of estrogenic regulation is that it is affected by a wide variety of non-steroidal compounds in addition to the ...
C Y, Meyers, H G, Lutfi, S, Adler
openaire +2 more sources
Estrogen receptor (ER), a member of the nuclear receptor superfamily, exerts prominent physiological roles in both humans and other species by acting directly as a transcription factor, altering nuclear gene expression. One peculiarity of estrogenic regulation is that it is affected by a wide variety of non-steroidal compounds in addition to the ...
C Y, Meyers, H G, Lutfi, S, Adler
openaire +2 more sources
1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
openaire +1 more source
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
openaire +1 more source
The synthesis of non-steroidal estrogen receptor binding compounds labeled with 80mBr
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1986Estrogen receptor (ER) binding radiopharmaceuticals have potential for use in the diagnosis and treatment of cancers of the female reproductive system. Two triphenylethylene derivatives based on the structure of hydroxytamoxifen 4, a high ER binding metabolite of tamoxifen 5, have been prepared: 1-(4-dimethylaminoethoxy)phenyl]-1-(4-hydroxy)phenyl-2 ...
R H, Seevers +3 more
openaire +2 more sources
Non-Steroidal Subtype Selective Estrogens
Current Medicinal Chemistry, 2005The biological effects of estrogens are thought to be mediated by two receptors referred to as ERalpha and ERbeta. In recent years significant efforts have been devoted to the design of subtype selective ligands. These ligands are valuable tools to establish the precise biological role of each of the subtypes and to develop new generations of ...
openaire +2 more sources