Results 231 to 240 of about 160,774 (316)

Supplementing Single‐Arm Trials with External Control Arms—Evaluation of German Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
As single‐arm trials (SATs) are increasingly used in pharmaceutical research, the validity of such study designs needs to be critically assessed. We characterize the feasibility of supplementing SATs with real‐world data (RWD)‐derived external control arms by determining the proportion of SATs on breast cancer and amyotrophic lateral sclerosis (ALS ...
Martin Russek, Jonas Peltner, Britta Haenisch   +2 more
wiley   +1 more source

Sex still matters for the brain and mental health across the lifespan. [PDF]

Biol Sex Differ
Beltz AM, Tronson NC, Singh M, Rezq S.
europepmc   +1 more source

Studies on the estrogen metabolism in human placenta

, 1957
F Akasu, Hiroshi Oki, Yoko Teshima
openalex   +2 more sources

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Impact of Sexual Dimorphism on Therapy Response in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: From Conventional and Nutritional Approaches to Emerging Therapies. [PDF]

Nutrients
Dileo E, Saba F, Parasiliti-Caprino M, Rosso C, Bugianesi E.   +4 more
europepmc   +1 more source

Synthesis of Azophenolcarboxylic Acids and their Estrogenic Activities. I. Synthesis.

, 1956
野村 祐次郎
openalex   +2 more sources

Estrogene [PDF]

, 2018
openaire   +1 more source

Determination of Hormonal Growth Promotants in Beef Using Liquid Chromatography–Tandem Mass Spectrometry

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed and validated to detect 12 synthetic or endogenous hormonal growth promotants commonly utilized in the livestock industry in the United States at low pg/mg concentrations. ABSTRACT Hormonal growth promotants (HGPs) are a class of pharmaceutical agents commonly administered to cattle in the United States to improve ...
Mary Mosburg, Yajing Li, Emily Helmes, Tara D. Falt, Josephine F. Trott, Gina Solomon, Russell C. Hovey, Benjamin C. Moeller   +7 more
wiley   +1 more source

Exploring the effects of estrogen deficiency and aging on organismal homeostasis during menopause. [PDF]

Nat Aging
Camon C, Garratt M, Correa SM.
europepmc   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source