Results 231 to 240 of about 162,839 (298)

Real‐world treatment patterns among patients diagnosed with hormone receptor‐positive metastatic breast cancer in the USA

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clinical guidelines for breast cancer management have evolved in the past decade. However, limited evidence exists regarding uptake of novel drug classes in management of hormone receptor‐positive (HR+) metastatic breast cancer (MBC) in the USA and whether disparities exist by race and ethnicity.
Kexin Zhu   +4 more
wiley   +1 more source

Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang   +9 more
wiley   +1 more source

Steroid hormones and influence of therapeutic drugs in Chinese postmenopausal rheumatoid arthritis patients. [PDF]

open access: yesFront Immunol
Zhang YY   +8 more
europepmc   +1 more source

Estrogene [PDF]

open access: yes, 2018
openaire   +1 more source

Neck‐vein thrombosis during spaceflight

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

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