Results 171 to 180 of about 50,471 (193)
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Enterohepatic cycling of 3H-estrone in the bull: Identification of estrone-3-glucuronide
Journal of Steroid Biochemistry, 1975Abstract Following surgical preparation of a bull with indwelling catheters in the gallbladder and duodenum, the animal was injected with radio-estrone. Bile was collected. Subsequently, this bile containing radioactive metabolites, all of which appeared to be conjugated with glucuronic acid, was infused into the duodenum.
Benjamin S. Leung +2 more
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ChemInform Abstract: An Estrone‐Glucuronide Conjugate.
ChemInform, 1997AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Joyce M. Waters +3 more
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Metabolism of radioactive estrone by rats
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1970Abstract 1. 1. 2-Hydroxyestrone “glucuronide” was found to be the major urinary metabolite of radioactive estrone from female Wistar rats. 2. 2. No radioactive estrone, estradiol-17β, 2-methoxyestrone, 2-methoxy-estradiol-17β or 2-hydroxyestradiol-17β could be detected after β-glucuronidase treatment of the urine.
Kenneth I.H. Williams, William B. Keith
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Chiral Hydrogenation of Estrone and Estrone-3-Methyl Ether
1995We have previously studied the use of enantiomeric chiral reducing agents in solution to control the direction of the hydrogenation of the keto group of estrone and estrone-3-methyl ether [1]. The complex catalysts chiral hydrosilane-rhodium-( +)- or (-)-DIOP or (+)- or (-)-BINAP allowed different stereoselectivities in the formation of the 17α- and ...
Gy. Göndös +3 more
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Tetrahedron Letters, 1988
Abstract The tricyclic ketone 5 has been condensed with the magnesium salt of the cyclopropanone hemiketal 6 to give the cyclopropanol 2 , readily converted to Torgov's compound 3 and then to(±)estrone 4 .
N. M. Sunder, N. S. Narasimhan
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Abstract The tricyclic ketone 5 has been condensed with the magnesium salt of the cyclopropanone hemiketal 6 to give the cyclopropanol 2 , readily converted to Torgov's compound 3 and then to(±)estrone 4 .
N. M. Sunder, N. S. Narasimhan
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The measurement of estrone sulfate in plasma
Steroids, 1971Abstract Estrone sulfate in plasma has been measured by extraction of the conjugate, solvolysis and radioimmunoassay of estrone. Plasma concentrations are: men, 330 pg/ml; women, follicular phase, 467 pg/ml; women, luteal phase, 891 pg/ml.
Mortimer B. Lipsett +2 more
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Irradiation of estrone in aqueous solutions
The International Journal of Applied Radiation and Isotopes, 1967Abstract The radiolysis of estrone in 1N sodium hydroxide gave predominately 2-hydroxyestrone, with a G(−M) of 1.14. Estradiol similarly afforded 2-hydroxyestradiol (G(−M) of 1.54). In 80% acetic acid estrone and estrone acetate gave small amounts of 2- and 4-hydroxilated compunds, while estrone formed a small amount of 2-hydroxyestrone in 90% acetic
O.H. Wheeler, R. Montalvo
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Estrone Sulfatase and Its Inhibitors
Anti-Cancer Agents in Medicinal Chemistry, 2009A high proportion (∼40%) of breast cancers are hormone-dependent and it is the female hormone estradiol (E2) that is believed to play a key role in the initiation, promotion and progression of this disease. In the fight against this disease, compounds which are potent inhibitors of the cytochrome P-450 enzyme aromatase (AR) (which catalyses the ...
Sabbir Ahmed +3 more
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Leptin enhances the synthesis of oleoyl-estrone from estrone in white adipose tissue
European Journal of Nutrition, 1999Oleoyl-estrone elicits powerful slimming effects on lean and obese rats, sparing protein, lowering appetite and maintaining energy expenditure. Leptin synthesis is markedly reduced by oleoyl-estrone. However, this effect is not observed in the obese Zucker fa/fa rats; these rats do not fully respond to leptin but they lose fat under oleoyl-estrone ...
Marià Alemany +6 more
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Formal Enantioselective Synthesis of (+)-Estrone
Organic Letters, 2007A formal total synthesis of (+)-estrone (4% overall yield; ca. 12 steps) could be achieved via the Torgov diene. An asymmetric allylic substitution is the key step for the construction of the chiral quaternary carbon center of a synthetic intermediate which was converted in four steps to the Torgov diene. [reaction: see text]
Paul Knochel, Darunee Soorukram and
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