Results 111 to 120 of about 29,178 (233)

Gestational Feed Restriction Induces Differential Expression of Novel Long Non‐Coding RNAs in Offspring Skeletal Muscle

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT This study aimed to investigate how maternal feed restriction at different gestational stages alters the expression of novel long non‐coding RNAs (lncRNAs) in the skeletal muscle of goat offspring. LncRNAs are emerging as important regulators of biological processes, including myogenesis, yet their role in fetal programming remains largely ...
Maria M. M. Muniz, Thaís C. Costa, Lívia S. Rodrigues, Luiza V. Kladt, Luiz Jardel M. Motta, Mariana M. Lopes, Nicola V. L. Serão, Mateus P. Gionbelli, Marcio Duarte   +8 more
wiley   +1 more source

Maternal and Early Developmental Effects of Perinatal Exposure to Therapeutically Relevant Doses of Common Nonsteroidal Anti‐Inflammatory Drugs in Rats

Birth Defects Research, Volume 118, Issue 8, August 2026.
ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used during pregnancy, yet information on their developmental safety during sensitive perinatal windows remains limited. This study evaluated the maternal and early developmental effects of paracetamol/acetaminophen, aspirin, and nimesulide administered at therapeutically ...
Sara Tawany Caetano dos Santos, Reggina Lorena Mellado Castro, Luara Magalhães, Giovanna Ferrari Rosalem, Julia Vitoria Francisco de Aquino, Otávio Galassi Vitale, Livia Trippe Nagaoka, Julia Stein, Beatriz de Matos Manoel, Bárbara Campos Jorge, Arielle Cristina Arena   +10 more
wiley   +1 more source

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source

Parity and Season Affect the Performance of an Automated Activity Monitoring System for Estrus Detection in Grazing Girolando Cows. [PDF]

Vet Med Int
Oliveira SAS, Figueiredo RA, Viana JHM, Féres LLDS, Féres LFR, Santos RMD, Martins CF, Ferreira IC.   +7 more
europepmc   +1 more source

SARS‐CoV‐2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Pain is a common neurological manifestation of COVID‐19, yet the mechanisms by which SARS‐CoV‐2 spike protein fragments contribute to nociceptive processing remain poorly understood. We investigated whether spike‐derived peptides directly activate spinal neuroimmune pathways involved in pain signalling.
Bruno Eduardo Silva, Rayner Ribeiro Cardoso, Lívia Maria Ribeiro Rosário, João Paulo Prado, Rafaela Silva dos Santos, Flávio Protasio Veras, Mylena de Souza, Eduardo Maffud Cilli, Danilo Olivier, Marco Antonio de Andrade Belo, Ives Charlie‐Silva, Ester Siqueira Caixeta, Angel Roberto Barchuk, Albená Nunes‐Silva, Thiago Roberto Lima Romero, Giovane Galdino   +15 more
wiley   +1 more source

Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study. [PDF]

Vet Anim Sci
Navidifar P, Kaveh A, Hosseini SE, Keshtkar Zolghadr H, Simiyari R, Taghinasab S, Salehi MS, Kahyani A.   +7 more
europepmc   +1 more source

Ameliorative Effects of Silymarin on Ovarian Ischemia/Reperfusion Injury via Modulation of Oxidative Stress and Inflammatory Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This study investigates the protective effects of SLY against experimental ovarian ischemia/reperfusion (OIR) injury. Findings demonstrate that SLY significantly attenuates oxidative stress and inflammatory response by reducing pro‐inflammatory cytokines and lipid peroxidation while preserving histological tissue integrity and enhancing antioxidant ...
Saime Ozbek Sebin, Basak Gulakar, Ayhan Tanyeli, Mustafa Can Guler, Elif Erbas, Yasin Bayır, Emir Enis Yurdgulu, Selim Comakli, Özlem Erdemci   +8 more
wiley   +1 more source

Granulosa Cell Tumour in a Spayed Cat With Ovarian Remnant Syndrome and Hyperestrogenaemia Without Estrus Signs. [PDF]

Vet Med Sci
Shinoda H, Mori K, Mori H, Ishigaki K, Asano K.   +4 more
europepmc   +1 more source

Sex‐Specific Anti‐Inflammatory Effects of Alternate Day Fasting via TLR4 and Leptin Signaling in Middle‐Aged Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ADF downregulates TLR4, reducing hypothalamic and hepatic inflammation, with stronger effects in females. ADF enhances leptin sensitivity in aging by reducing SOCS3 and upregulating ObRb, thereby improving metabolic function. ADF reduces retroperitoneal fat and glucose levels, with females experiencing greater fat loss.
Ozgen Kilic‐Erkek, Gulsah Gundogdu, Abdullah Coguplugil, Yavuz Dodurga   +3 more
wiley   +1 more source

Effects of Summer Heat Stress on Physiological Parameters and Reproductive Efficiency of Barbarine Ewes Under Natural Outdoor or Indoor Conditions

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 686-697, August 2026.
ABSTRACT Climate change and rising ambient temperatures increasingly challenge sheep production systems in arid and semi‐arid regions, particularly during the summer breeding season. This study evaluated the effects of heat stress and direct solar exposure on physiological responses, metabolic profile, and reproductive performance of Barbarine ewes, a ...
Samia Khnissi, Dorra Aouadi, Hela Chalouati, Mourad Rekik, Imène Ben Salem   +4 more
wiley   +1 more source