Results 91 to 100 of about 1,697 (183)
Camouflaged Sepsis: How ETBF Cleavage Transforms Antivirals into Multi-Organ Toxins
In high-acuity clinical environments, multi-organ dysfunction syndrome (MODS) is traditionally attributed to primary viral or bacterial pathogenesis. This perspective paper introduces a complex systems-safety forensic framework evaluating a hidden metabolic failure pathway where host tissue, the intravenous 1′-cyano-substituted adenosine analogue ...
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Medycyna doswiadczalna i mikrobiologia, 2003 Prevalence of enterotoxin producing Bacteroides fragilis (ETBF) strains in faecal samples of children with clinical diagnosis antibiotic associated diarrhoea (AAD) was investigated. Out of faecal samples collected from sixty children, thirty C. difficile strains were isolated. Enterotoxigenic B.
Hanna, Pituch +3 more
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In Vitro Evaluation of Propolis Effects on Bacteroides fragilis Toxin-mediated Inflammatory Pathways
Korean Journal of Clinical Laboratory ScienceColorectal cancer (CRC) remains a significant global health concern because of its increasing incidence and mortality rates. Chronic intestinal inflammation is a critical driver in the pathogenesis of CRC, particularly in individuals with inflammatory ...
Soonjae HWANG, Yeram LEE, Ki-Jong RHEE
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Pharmacological ResearchCachexia affects approximately 50–80 % of advanced cancer patients, particularly those with gastric cancer (GC). Therefore, early detection of cachexia is essential to prevent its progression.
Jian Wu +11 more
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, 2015 Mitigation of IL-17 response to ETBF in absence of Tregs is not restricted to CD4+ (Th17) cells.. B6.Foxp3DTR mice were inoculated with ETBF. Either 150 μl purified sterile H2O or 50 ng/g DT was administered ip on days -2, -1, 1, 3, & 5.
Xinqun Wu (11611624) +8 more
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Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming.
PLoS ONEFusobacterium nucleatum (Fn) and enterotoxigenic Bacteroides fragilis (ETBF) are two pathobionts consistently enriched in the gut microbiomes of patients with colorectal cancer (CRC) compared to healthy counterparts and frequently observed for their ...
Josh Jones +3 more
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Dissecting Gut‐Microbial Community Interactions using a Gut Microbiome‐on‐a‐Chip
Advanced ScienceWhile the human gut microbiota has a significant impact on gut health and disease, understanding of the roles of gut microbes, interactions, and collective impact of gut microbes on various aspects of human gut health is limited by the lack of suitable ...
Jeeyeon Lee +2 more
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Abstract Modern metabolic disease is classically framed as a behavioral pathology driven by caloric surplus and sedentary lifestyles—an institutional narrative that subtly shifts systemic failure onto the individual. This paper challenges this paradigm by introducing an alternative, highly integrated systems-biology model: an engineered chemical and ...
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Anti-ETBF = "Anti-aging"? Breaking the Microbial Loop of Human Mortality through Anti-Aging Vaccines
Title Anti-ETBF = Anti-aging? Breaking the Microbial Loop of Human Mortality through Anti-Aging Vaccines Description / Abstract This theoretical paper introduces a disruptive biological synthesis that redefines human aging and systemic mortality not as stochastic wear-and-tear, but as an ...
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Mechanistic diversity of Bacteroides fragilis toxins and neutralization with single domain antibody
: Enterotoxigenic Bacteroides fragilis (ETBF) promotes colonic inflammation by secreting metalloenzyme toxins (BFTs). Understanding BFT mechanisms and developing neutralization strategies is critical.
He, Wenbo +10 more
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