Results 101 to 110 of about 1,697 (183)

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

, 2016
BACKGROUND: Chronic inflammation and composition of the colon microbiota have been associated with colorectal cancer in humans. The human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel disease and colorectal
Sears, Cynthia L., Van Meerbeke, Sara W., Housseau, Franck, Casero, Robert A., Jr., Shields, Christina E. DeStefano, O’ Hagan, Heather M., Wang, Hao, Huso, David L.   +7 more
core   +1 more source

An enteropathogenic microbial toxin modulates the breast cancer epigenome resulting in concurrent silencing of tumor suppressor genes

Breast Cancer Research
Background Recent studies have determined a close association between host microbiota and breast cancer initiation, growth and therapeutic outcomes.
Deepak Verma, Deeptashree Nandi, Sheetal Parida, Archisha Saxena, Dipali Sharma   +4 more
doaj   +1 more source

Proliferating TA cells 2, similar to CSC-like TA cells in notable disease associations, diverge at the gene and pathway levels.

(A) The TA cells depicted here are the 4 subclusters of the complete TA cell population and are an aggregate from all mouse samples (ApcMin/+ mice treated with PBS, Fn or ETBF and wild type mice treated with PBS, Fn or ETBF.
Ilana L. Brito (16327695), Rahul R. Nath (17980108), Qiaojuan Shi (6611735), Josh Jones (17980105)   +3 more
core   +1 more source

ZINC and CANCER: How Enterotoxigenic Bacteroides fragilis (ETBF) Alters Zinc Transporter Dynamics Across Divergent Carcinomas

Title: Systemic Nutritional Immunity and Pathogenic Zinc Theft: How Enterotoxigenic Bacteroides fragilis (ETBF) Alters Zinc Transporter Dynamics Across Divergent Carcinomas.   Short Description: Why do some cancers hoard zinc while others completely purge it? This paper unmasks an unseen variable: systemic zinc-theft driven by the gut pathobiont ETBF.
openaire   +2 more sources

A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues

Nature Communications
Efficient interbacterial competitions and diverse defensive strategies employed by various bacteria play a crucial role in acquiring a hold within a dense microbial community.
Ming Tong, Jinghua Xu, Weixun Li, Kun Jiang, Yan Yang, Zhe Chen, Xuyao Jiao, Xiangfeng Meng, Mingyu Wang, Jie Hong, Hongan Long, Shuang-Jiang Liu, Bentley Lim, Xiang Gao   +13 more
doaj   +1 more source

Virulence of Enterotoxigenic Bacteroides Fragilis (ETBF) Strains is B. Fragilis Toxin (BFT) Isoform Dependent

Gastroenterology, 2011
Shaoguang Wu, Kenolisa Onwueme, XinQun Wu, Guillermo Ortega, Augusto Franco-Mora, Franck Housseau, Drew M. Pardoll, Cynthia L. Sears   +7 more
openaire   +1 more source

The Metabolic Nexus of Indigenous Health Disparities: Exploring the Intersecting Roles of Enterotoxigenic Bacteroides fragilis (ETBF), Thiamine, and Niacin

Title The Metabolic Nexus of Indigenous Health Disparities: Exploring the Intersecting Roles of Enterotoxigenic Bacteroides fragilis (ETBF), Thiamine, and Niacin   Description / Abstract This position paper outlines a novel, unified biochemical paradigm to explain the persistent disparities in acute and chronic disease burdens between First ...
openaire   +1 more source

The ETBF-Endocrine Respiration Loop: How Living Enterotoxigenic Bacteroides fragilis Exploits Host Steroid Shunts to Drive Pseudohypoxia, Field Cancerization, and Endocrine Therapy Resistance

The ETBF-Endocrine Respiration Loop: How Living Enterotoxigenic Bacteroides fragilis Exploits Host Steroid Shunts to Drive Pseudohypoxia, Field Cancerization, and Endocrine Therapy Resistance   Description / Abstract Field: This paper presents a groundbreaking, closed-loop translational model of microbial endocrinology that redefines our ...
openaire   +2 more sources

Immunofluorescence Microscopic Evaluation of Tight Junctional Proteins during EnterotoxigenicBacteroides fragilis(ETBF) Infection in Mice

Biomedical Science Letters, 2018
Soonjae Hwang, Yeowool Kang, Minjeong Jo, Sung Hoon Kim, Won Gil Cho, Ki-Jong Rhee   +5 more
openaire   +2 more sources

Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min ( Apc ^+/- ) mice: a human commensal-based murine model of colon carcinogenesis [PDF]

Cell Cycle, 2010
Franck, Housseau, Cynthia L, Sears
openaire   +2 more sources