Results 51 to 60 of about 1,697 (183)
Cancer Nexus, Volume 2, Issue 4, October 2026.Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang +7 more
wiley +1 more source
NTBF strain NCTC 9343 outcompetes ETBF strains and secretes a growth-inhibitory protein.
, 2016 (A) In vitro competition assay. Strain NCTC 9343 was co-cultivated with one ETBF strain and passaged after 24 h. The competitive index (CI, ratio of ETBF/NCTC 9343 DNA) was determined by strain-specific qPCR.
Harris D. Bernstein (690540) +1 more
core +1 more source
Gastrointestinal Pathobionts in Pediatric Crohn’s Disease Patients
International Journal of Microbiology, 2018 Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal tract, with a rising incidence worldwide, particularly in children. CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has recently
Rachel V. Purcell +4 more
doaj +1 more source
Viruses, 2021 Since the beginning of the 20th century, bacteriophages (phages), i.e., viruses that infect bacteria, have been used as antimicrobial agents for treating various infections. Phage preparations targeting a number of bacterial pathogens are still in use in
Nata Bakuradze +12 more
doaj +1 more source
Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
MedComm, Volume 7, Issue 10, October 2026.The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
ETBF strains secrete variable amounts of mature Bft.
, 2016 Culture supernatants were obtained from ETBF strains at the indicated growth phases. The volume of each supernatant was normalized based on cell number (OD600) and proteins were concentrated 40-fold.
Harris D. Bernstein (690540) +1 more
core +1 more source
Repositioning small molecule drugs as allosteric inhibitors of the BFT‐3 toxin from enterotoxigenic Bacteroides fragilis [PDF]
, 2022 Bacteroides fragilis is an abundant commensal component of the healthy human colon. However, under dysbiotic conditions, enterotoxigenic B. fragilis (ETBF) may arise and elicit diarrhea, anaerobic bacteremia, inflammatory bowel disease, and colorectal ...
Eckhard, Ulrich +19 more
core +1 more source
Scientific Reports, 2017 Numerous studies are devoted to the intestinal microbiota and intercellular communication maintaining homeostasis. In this regard, vesicles secreted by bacteria represent one of the most popular topics for research.
Natalya B. Zakharzhevskaya +12 more
doaj +1 more source
iMetaMed, Volume 2, Issue 3, September 2026.Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo +4 more
wiley +1 more source
Korean Journal of Clinical Laboratory Science, 2023 Enterotoxigenic Bacteroides fragilis (ETBF) has been reported to promote colitis and colon cancer through the secretion of B. fragilis toxin (BFT), a zinc-dependent metalloprotease. In colonic epithelial cells, BFT induces the cleavage of E-cadherin into
Da-Hye KANG +3 more
doaj +1 more source