Results 61 to 70 of about 1,697 (183)

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

[The relationship of enterotoxigenic bacteroides fragilis and fusobacterium nucleatum intestinal colonization with colorectal cancer: a case-control study performed with colon biopsies]

, 2023
In recent years, it has been shown that some bacteria may be associated with colorectal cancer (CRC). In this study, it was aimed to investigate the role of Fusobacterium nucleatum and enterotoxigenic Bacteroides fragilis (ETBF) in the etiology of CRC by
Kepil, Nuray, Taner, Zeynep, Tokuç, Edip, Taşkı, İhsan, Demirci, Mehmet, Kılınçarslan, Ayşe Ceylan, Tokman, Hrisi Bahar, Kocazeybek, Bekir Sami, Bakar, Murat Tuğberk, Öztürk Bakar, Yeşim, Demiryas, Süleyman, Ziyad, Muhuyedin Abdırahman, Bahar Tokman, Hrisi, Ceylan Kılınçarslan, Ayşe, Taşçı, İhsan   +14 more
core   +1 more source

The association between fecal enterotoxigenic B. fragilis with colorectal cancer

BMC Cancer, 2019
Background Enterotoxigenic Bacteroides fragilis (ETBF) is an enterotoxin-producing bacterium that possibily has a role in the occurrence and progression of colorectal cancer (CRC) by modulating the mucosal immune response and inducing epithelial cell ...
Fakhri Haghi, Elshan Goli, Bahman Mirzaei, Habib Zeighami   +3 more
doaj   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

ETBF and afaC+ E. coli are significantly more prevalent in colon vs. rectal cancers.

, 2015
This applies to both tumour and normal tissue in the case of ETBF (FDR = 0.002, 0.001, respectively) and normal tissue only in the case of afaC (FDR = 0.03).
Amirtha Dakshinamurthy (699588), Jonathan M. Blackburn (699590), Paul Goldberg (699589), Katie S. Viljoen (699587)   +3 more
core   +1 more source

Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1338-1352, July 2026.
Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan, Khushbakhat Alia, Yusra Al Dhaheri, Muhammad Naseem, Rabah Iratni, Edgar Serfling, Khalid Muhammad   +6 more
wiley   +1 more source

How Host Phylogeny, Diet, and Habitat Affect Gut Microbial Diversity in Wild Snakes

Ecology and Evolution, Volume 16, Issue 7, July 2026.
Gut microbiota plays critical roles in host digestion, immune regulation, neurochemical signaling, and metabolic homeostasis. Based on wild snakes (73 individuals from 23 species) from China, we explored the composition, characteristics, and functions of gut microbes across different groups using fecal metagenomic samples; further we explored the ...
Jiaqi Zhang, Chunmei Fu, Songwen Tan, Bing Lyu, Guocheng Shu, Lei Shi, Yayong Wu, Peng Guo   +7 more
wiley   +1 more source

ETBF strains exhibit enhanced biofilm formation.

, 2016
(A) B. fragilis strains forming biofilms in microtiter plates were stained with crystal violet and quantified at A570. A single strain or a combination of three ETBF strains (2-078382-3, 20793–3, and 20656-2-1) was grown in BHIS medium, in co-culture ...
Harris D. Bernstein (690540), Jessica V. Pierce (3162873)   +1 more
core   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Gut Microbiota and Extraintestinal Cancers: Mechanistic Insights and Microbiome‐Targeted Interventions

JGH Open, Volume 10, Issue 5, May 2026.
ABSTRACT The gut microbiota is a dynamic community of bacteria, viruses, fungi, and archaea that plays a pivotal role in regulating host immunity, metabolism, and systemic homeostasis. Dysbiosis, characterized by an imbalance in the microbial composition, is being increasingly recognized as a contributor not only to gastrointestinal cancers but also to
Rishi Chowdhary, Manjeet Kumar Goyal, Kirti Arora, Tanisha Sehgal, Prachi Dawer, F. N. U. Anirudh, Jeffrey Berinstein, Shrinivas Bishu, Laurie Matt‐Amaral   +8 more
wiley   +1 more source