Results 81 to 90 of about 42,722 (256)

Analysis of Isoniazid, Streptomycin and Ethambutol resistance in Mycobacterium tuberculosis isolates from Morocco

open access: yesJournal of Infection in Developing Countries, 2009
Background: Drug-resistant tuberculosis is a major problem worldwide. Based on the knowledge of specific mutations occurring in Mycobacterium tuberculosis genome, drug resistance can be detected earlier.
Imane Chaoui   +8 more
doaj   +1 more source

Neurotoxicity [PDF]

open access: yes, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust   +15 more
core   +2 more sources

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami   +9 more
wiley   +1 more source

Idiopathic AIDS enteropathy and treatment of gastrointestinal opportunistic pathogens. [PDF]

open access: yes, 2009
Diarrhea in patients with acquired immune deficiency syndrome (AIDS) has proven to be both a diagnostic and treatment challenge since the discovery of the human immunodeficiency virus (HIV) virus more than 30 years ago.
Cello, John P, Day, Lukejohn W
core  

A 37-year-old woman presenting with impaired visual function during antituberculosis drug therapy: a case report [PDF]

open access: yes, 2011
Introduction Combination antituberculosis drug therapy remains the mainstay of treating tuberculosis. Unfortunately, antituberculosis drugs produce side effects including (toxic) impaired visual function, which may be irreversible.
Abdulkabir A Ayanniyi   +1 more
core   +1 more source

A Rapid Assessing Method of Drug Susceptibility Using Flow Cytometry for Mycobacterium tuberculosis Isolates Resistant to Isoniazid, Rifampin, and Ethambutol [PDF]

open access: diamond, 2022
Sun-Kyoung Lee   +7 more
openalex   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 608-617, May 2026.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp   +6 more
wiley   +1 more source

Kutane Infektionen mit nicht‐tuberkulösen Mykobakterien: eine retrospektive Studie mit 94 Fällen aus Deutschland

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 608-618, May 2026.
Zusammenfassung Hintergrund Kutane nichttuberkulöse Mykobakterien‐Infektionen (NTM) sind diagnostisch und therapeutisch herausfordernd. Ziel dieser Studie war die Charakterisierung kutaner NTM‐Infektionen in Deutschland über einen Zeitraum von 24 Jahren. Patienten und Methodik Eingeschlossen wurden 73 Patienten mit kutanen NTM‐Infektionen, die zwischen
Luisa Bopp   +6 more
wiley   +1 more source

Detection of Ethambutol-Resistant Associated Mutations in Mycobacterium tuberculosis Isolates from Iran Using Multiplex Allele-Specific PCR

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2013
Tuberculosis is a serious global public health problem and its high prevalence is stron gly associated with the enhancement of drug resistance. In this study we demonstrate a multiplex allele-specific polymerase chain reaction (MAS)-PCR assay to ...
Somayeh Bahrami   +4 more
doaj  

Current and emerging treatment strategies for Mycobacterium avium complex pulmonary disease: a narrative review [PDF]

open access: yesThe Ewha Medical Journal
The Mycobacterium avium complex (MAC), comprising M. avium and M. intracellulare, constitutes the predominant cause of nontuberculous mycobacterial pulmonary disease (NTM-PD) in Korea, followed by the M. abscessus complex.
Chiwook Chung
doaj   +1 more source

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