Results 61 to 70 of about 25,028 (165)

A prospective study on the effect of ethambutol on retinal nerve fiber layer thickness and central macular thickness

Journal of Clinical Ophthalmology and Research
Background: Ethambutol-induced optic neuropathy is a sight-threatening side effect seen in patients receiving antitubercular drugs. The prevalence is estimated to be about 1%–2%.
Sanchari Sarkar, Sanjay Kumar Daulat Thakur, Aparup Dhua, Avik Dey Sarkar, Payel Khatua   +4 more
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Apoptosis-Inducing Action of Antituberculosis Drugs of the Main Group in Vitro

Антибиотики и Химиотерапия, 2020
The influence of the main antituberculosis drugs (isoniazid, rifampicin, ethambutol) on in vitro apoptosis of peripheral blood lymphocytes from patients with pulmonary tuberculosis was researched.
O. A. Vasilyeva, V. A. Serebryakova, O. I. Urazova, V. V. Novitsky, T. E. Kononova, I. O. Naslednikova   +5 more
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Anti-tuberculosis medication-induced oculogyric crisis and the importance of proper history taking

International Medical Case Reports Journal, 2017
Lin Ho Wong,1 Endean Tan2 1University College Cork, Cork, Ireland; 2Tan Tock Seng Hospital, Singapore Abstract: Oculogyric crisis (OGC), frequently caused by medications such as antiemetics, antidepressants, and anti-epileptics, is an acute dystonic ...
Wong LH, Tan E
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Clinical profile and visual outcomes in ethambutol-induced toxic optic neuropathy

Indian Journal of Ophthalmology
Purpose: To characterize the severity of vision loss, dose-related adverse effects, and visual outcomes in ethambutol-induced toxic optic neuropathy (ETON) patients.
Jenil Sheth, Virender Sachdeva, Ashima Goyal, Aditi Parikh, Rohan Nalawade, Hardik Nanavati, Ramesh Kekunnaya   +6 more
doaj   +1 more source

Nationwide usage of ethambutol and incidence and screening practices of optic neuropathy

Frontiers in Pharmacology
IntroductionEthambutol, a key anti-tuberculosis medication, is associated with optic neuropathy, which can lead to significant vision impairment. This population-based cohort study investigated the nationwide usage of ethambutol and the incidence and ...
Jiyeong Kim, Hyeon Yoon Kwon, Seong Joon Ahn   +2 more
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A Case Report of Ethambutol Toxic Optic Atrophy

مجله دانشکده پزشکی اصفهان, 2011
In this paper, we present a case with acute vision loss due to ethambutol therapy. A sixty-three year-old man underwent tuberculosis treatment (Ethambutol, Izoniazid, Rifampicin, Pirazin Amid) six years before this report.
Gholamali Naderian, Hamid Fesharaki, Mohammad Ghoraishi, Valleh Sajjadi   +3 more
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Flow injection analysis of ethambutol in synthetic urine using a graphite-polyurethane composite electrode as an amperometric detector

Open Chemistry, 2013
Perantoni Camila, Azevedo Alessandra, Vaz Fernando, Oliveira Marcone, Matos Renato, Lowinsohn Denise   +5 more
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Mutations in embB406 Are Associated with Low-Level Ethambutol Resistance in Canadian Mycobacterium tuberculosis Isolates

Antibiotics
In Mycobacterium tuberculosis, molecular predictions of ethambutol resistance rely primarily on the detection of mutations within embB. However, discordance between embB406 mutations and gold standard phenotypic drug sensitivity testing (DST) questions ...
Morgan Hiebert, Meenu K. Sharma, Melissa Rabb, Lisa Karlowsky, Kiana Bergman, Hafid Soualhine   +5 more
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Development of Co-Amorphous Systems for Inhalation Therapy—Part 1: From Model Prediction to Clinical Success

Pharmaceutics
Background/Objectives: The integration of machine learning (ML) and artificial intelligence (AI) has revolutionized the pharmaceutical industry by improving drug discovery, development and manufacturing processes.
Eleonore Fröhlich, Aurora Bordoni, Nila Mohsenzada, Stefan Mitsche, Hartmuth Schröttner, Sarah Zellnitz-Neugebauer   +5 more
doaj   +1 more source

Baseline Retinal Nerve Fiber Layer Thickness and Visual Outcomes of Eyes with Ethambutol Toxic Optic Neuropathy

Philippine Journal of Ophthalmology, 2018
Objectives: To determine the retinal nerve fiber layer thickness (RNFL) in eyes with ethambutol-induced toxic optic neuropathy (ETON) at the time of diagnosis and to describe the visual outcomes at 1, 3, and 6 months after discontinuation of ethambutol.
Franz Marie Cruz, MD, DPBO
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