Results 111 to 120 of about 4,165 (263)

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Human gut microbiota and their production of endocannabinoid-like mediators are directly affected by a dietary oil

Gut Microbes
Dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) and the gut microbiome affect each other. We investigated the impact of supplementation with Buglossoides arvensis oil (BO), rich in stearidonic acid (SDA), on the human gut microbiome.
Charlène Roussel, Mathilde Sola, Jacob Lessard-Lord, Nayudu Nallabelli, Pamela Généreux, Camille Cavestri, Oumaima Azeggouar Wallen, Rosaria Villano, Frédéric Raymond, Nicolas Flamand, Cristoforo Silvestri, Vincenzo Di Marzo   +11 more
doaj   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

Small, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo, Gabrielle Coelho Lelis, Maria Luisa Braunger, Stefano Casalini, Yasmin Watanabe, Gabriel Ravanhani Schleder, Wilson Tiago Fonseca, Rafael Furlan de Oliveira   +7 more
wiley   +1 more source

Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells.

PLoS ONE, 2017
Tumour necrosis factor α (TNFα) is involved in the pathogenesis of prostate cancer, a disease where disturbances in the endocannabinoid system are seen.
Jessica Karlsson, Sandra Gouveia-Figueira, Mireille Alhouayek, Christopher J Fowler   +3 more
doaj   +1 more source

Oxidation of ethanolamines by sodium N-bromobenzenesulfonamide in alkaline buffer medium: A kinetic and mechanistic study

, 2001
The kinetics of oxidation of ethanolamines, monoethanolamine (MEA), diethanolamine (DEA), and triethanolamine (TEA), by sodium N-bromobenzenesulfonamide or bromamine-B (BAB) in alkaline buffer medium (pH 8.7-12.2) has been studied at 40°C.
Made Gowda, N.M., Vaz, N., Puttaswamy, .
core   +1 more source

Positive Aging‐Free Quantum Dot Light‐Emitting Diodes Enabled by Single‐Source Chloride‐Doped ZnMgO Electron Transport Layers

Small, EarlyView.
Single‐source chloride doping of ZnMgO electron‐transport layers (ETLs) intrinsically suppresses oxygen‐vacancy traps, eliminating storage‐driven positive aging in quantum dot light‐emitting diodes. Devices deliver day‐0 peak external quantum efficiency and longer operational lifetimes, while transport and interfacial photoluminescence remain time ...
Jaeyeop Lee, Yeyun Bae, Kyoungeun Lee, Woon Ho Jung, Hyeonjun Lee, Byong Jae Kim, Hyoungjun Kim, Keon Woo Kim, Byeong Guk Jeong, Jaehoon Lim, Jeongkyun Roh   +10 more
wiley   +1 more source

Structure of the Arabidopsis receptor kinase SRF6 ectodomain determined from crystals obtained using the LRR crystallization screen

Acta Crystallographica Section D, EarlyView.
A crystallization screen that has enabled the structural analysis of various extracellular domains of plant membrane receptor kinases is described together with the structure of the LRR domain of the receptor SRF6.Plant‐specific membrane receptor kinases with structurally diverse extracellular domains regulate key processes in plant growth, development,
Alberto Caregnato, Ulrich Hohmann, Michael Hothorn   +2 more
wiley   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

Allergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza, Siratcha Phanthong, Huey‐Jy Huang, Milena Weber, Eszter Sarzsinszky, Petra Zieglmayer, Gabrielle Pauli, Margarete Focke‐Tejkl, Mikhail Tulaev, Nikolina Todorovic, Walter Keller, Thomas Schlederer, Luis Caraballo, Anchalee Tungtrongchitr, Rudolf Valenta, Pongsakorn Tantilipikorn, Susanne Vrtala   +16 more
wiley   +1 more source

Improved prediction of symptomatic type 1 diabetes using a luciferase‐based assay to measure (pro)insulin autoantibodies

Diabetic Medicine, EarlyView.
Abstract Introduction Insulin autoantibodies (IAA) are key predictors of type 1 diabetes, particularly in young children. Micro‐radiobinding assays (RBA) are the gold standard for IAA measurement but have limitations. We assessed whether a luciferase immunoprecipitation system (LIPS) assay improved diabetes risk assessment.
Rebecca C. Wyatt, Cristina Brigatti, Sian L. Grace, Claire L. Williams, Ilaria Marzinotto, Ben T. Gillard, Elena Bazzigaluppi, Deborah Shoemark, Michela A.‐M. Chandler, Peter Achenbach, Lorenzo Piemonti, BOX Study Group, Isabel Wilson, Rachel Aitken, Ilana Kelland, Clare Megson, Chitrabhanu Ballav, Atanu Dutta, Michelle Russell‐Taylor, Rachel Besser, James Bursell, Shanthi Chandran, Sejal Patel, Anne Smith, Manohara Kenchaiah, Gomathi Margabanthu, Foteini Kavvoura, Chandan Yaliwal, AWAF, Rachel Aitken, Olivia Pearce, Sarah Stollery, Elinor Balch, Hanah Batholomew, Zhara Hashmi, Kathleen M. Gillespie, Vito Lampasona, Alistair J. K. Williams, Anna E. Long   +38 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source