Binary ethosomes for the enhanced topical delivery and antifungal efficacy of ketoconazole
OpenNano, 2023 This work aimed to prepare ketoconazole-loaded ethosomes and binary ethosomes to improve its skin delivery and antifungal efficacy. A 32 factorial design was used to optimize the ethosomes and formulate ketoconazole-loaded binary ethosomes. Ethosomes and
Mona Qushawy, Ghareb M Soliman
exaly +4 more sources
Design, characterization, and evaluation of eco-friendly etofenprox-loaded ethosomes to control Ceratitis capitata (Diptera: Tephritidae) [PDF]
Scientific ReportsCeratitis capitata, is one of the most considerable invasive pests affecting fruit production worldwide. Conventional pesticides are generally formulated using organic solvents and emulsifiers that, in turn, are flammable and toxic. Thanks to their small
Francesco Corrias +9 more
doaj +3 more sources
Mechanism investigation of ethosomes transdermal permeation
International Journal of Pharmaceutics: X, 2019 Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear.
Qiong Bian +2 more
exaly +5 more sources
Enhanced Anti-Melanoma Activity of Nutlin-3a Delivered via Ethosomes: Targeting p53-Mediated Apoptosis in HT144 Cells [PDF]
CellsThis study evaluated ethosomes as a novel nanodelivery system for nutlin-3a, a known MDM2 inhibitor and activator of the p53 pathway, to improve nutlin-3a’s poor solubility, limiting its bio-distribution and therapeutic efficacy.
Arianna Romani +12 more
doaj +3 more sources
A Newfangled Collagenase Inhibitor Topical Formulation Based on Ethosomes with Sambucus nigra L. Extract [PDF]
Pharmaceuticals, 2021 Sambucus nigra L. (S. nigra) is a shrub widespread in Europe and western Asia, traditionally used in medicine, that has become popular in recent years as a potential source of a wide range of interesting bioactive compounds.
Ana Henriques Mota +15 more
doaj +2 more sources
Ethosome-Based Transdermal Drug Delivery: Its Structural Components, Preparation Techniques, and Therapeutic Applications Across Metabolic, Chronic, and Oncological Conditions [PDF]
PharmaceuticsTransdermal drug delivery systems (TDDSs) provide a non-invasive alternative to oral and parenteral routes, delivering drugs into the bloodstream while avoiding gastrointestinal degradation and first-pass metabolism.
Rashed M. Almuqbil, Bandar Aldhubiab
doaj +2 more sources
Development of Ethosomes for the Topical Treatment of Androgenic Alopecia: Ethanol Effect on Dutasteride Targeting to the Hair Follicles [PDF]
PharmaceuticsBackground/Objectives: Treatment options for androgenic alopecia are still very limited and lack long-term efficacy. Dutasteride (DUT) has gained interest as a potent inhibitor of 5α-reductase, allowing for spaced applications, but DUT oral intake can ...
Jayanaraian F. M. Andrade +7 more
doaj +2 more sources
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies [PDF]
Scientific ReportsThe purpose of the current work was to develop and characterize ethosomes of vitamin D3 gel that could more effectively work against psoriasis. Psoriasis is a chronic immune-mediated inflammatory skin disease.
Yasir Mehmood +8 more
doaj +2 more sources
Potential of ethosomes for enhanced transdermal drug delivery in skin diseases [PDF]
Nanomedicine Journal, 2022 Ethosomes are novel ethanolic phospholipid vesicles which are significantly used for the transdermal drug delivery. Ethanol is an efficient permeation enhancer which is used in ethosomes about 20-45%.
Bhumika Kumar, Pravat Sahoo
doaj +1 more source
Ethosomes: a potential nanocarrier for transdermal drug delivery [PDF]
ERU Research Journal, 2023 Ethosomal system is a lipid vesicular nanocarrier that hold a high concentration of alcohols. These nanocarriers are optimized for the dermal and transdermal delivery of medicinal drugs with various physicochemical features.
Abdel-Hameed Abubakr +2 more
doaj +1 more source