Therapeutic and cosmeceutical potential of ethosomes: An overview
The main disadvantage of transdermal drug delivery is the poor penetration of most compounds into the human skin. The main barrier of the skin is located within its uppermost layer, the stratum corneum (SC).
Poonam Verma, K Pathak
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ETHOSOMES: A NOVEL APPROACH FOR THE DELIVERY OF DRUG
Background: In the past m8any years, there have been many studies that are considering the nanoparticles as the carriers of the drugs for improving the patient compliance. One such approach of delivery of the drug is through the ethosomes.
Muhammad Ahsan Waqar +3 more
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Positively Charged Lipid as Potential Tool to Influence the Fate of Ethosomes
Ethosomes® are one of the main deformable vesicles proposed to overcome the stratum corneum. They are composed of lecithin, ethanol and water, resulting in round vesicles characterized by a narrow size distribution and a negative surface charge.
Antonia Mancuso +4 more
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Ethosomes for Coenzyme Q10 Cutaneous Administration: From Design to 3D Skin Tissue Evaluation [PDF]
Ethosome represents a smart transdermal vehicle suitable for solubilization and cutaneous application of drugs. Coenzyme Q10 is an endogenous antioxidant whose supplementation can counteract many cutaneous disorders and pathologies.
Maddalena Sguizzato +9 more
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Formulation and in-vitro Evaluation of Ethosomes using Anastrozole as a Modeling Drug
Anastrozole (ANZ) is a potent non-steroidal aromatase II inhibitor (AI) used to decrease or delay the progression of breast tumor growth in some women. Since ANZ could be delivered transdermally due to its physicochemical characteristics as (log p of 3 ...
Neven Nasef AlEbadi +1 more
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Paeonol-Loaded Ethosomes as Transdermal Delivery Carriers: Design, Preparation and Evaluation
Paeonol exhibits a wide range of pharmacological activities, such as anti-inflammatory, antidiabetic as well as pain-relieving activities. However, its intrinsic properties, such as low water solubility, poor stability and low oral bioavailability ...
Hongdan Ma +5 more
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Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation. [PDF]
The aim of this study was to develop ethosomes loaded with cryptotanshinone (CPT) and formulate them as a topical gel for the treatment of acne. Ethosomes were prepared and evaluated for vesicle size, CPT loading and encapsulation efficiency.
Zhenwei Yu, Hongyan Lv, Gang Han, Ke Ma
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Preparation and In Vitro Evaluation of Tacrolimus-Loaded Ethosomes [PDF]
The main objective of the present work was to prepare and assess dermal delivery of tacrolimus-loaded ethosomes versus classic liposomes. Both delivery systems were characterized for particle size, polydispersity index, and entrapment efficiency (EE), by
Guiling Li +6 more
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Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
Yong-Tai Zhang, Li-Na Shen, Ji-Hui Zhao, Nian-Ping FengDepartment of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaAbstract: This study aimed to improve skin permeation and ...
Zhang YT, Shen LN, Zhao JH, Feng NP
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Ethosomes and organogels for cutaneous administration of crocin
The present study describes the production and characterization of phosphatidylcholine based ethosomes and organogels, as percutaneous delivery systems for crocin. Crocin presence did not influence ethosome morphology, while the drug slightly increased ethosome mean diameter.
Esposito E +6 more
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