Results 181 to 190 of about 30,453 (235)
Nature, 1995 The Ets-1 proto-oncogene is a member of a transcription factor family characterized by homology to the v-ets oncogene. In adult mice, Ets-1 is expressed predominantly in lymphoid cells where it has been implicated in regulating transcription of lymphocyte-specific genes.
Raphaël Borie +7 more
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Renal expression of proto-oncogene Ets-1 on matrix remodeling in experimental diabetic nephropathy
Acta Histochemica, 2010 The molecular mechanisms of glomerulosclerosis and tubulointerstitial fibrosis in diabetic nephropathy (DN) have received scant attention. Ets-1 proto-oncogene plays a role in matrix remodeling by regulating matrix-degrading enzymes. We investigated the possible role of Ets-1 in the pathogenesis of DN.
Dian-xin Liu +3 more
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ETS-1 proto-oncogene as a key newcomer molecule to predict invasiveness in laryngeal carcinoma
Pathology - Research and Practice, 2011 ETS-1 protein is one of the key regulators in tumor invasion and progression. We aimed to evaluate the role of ETS-1 in the invasiveness and progression of laryngeal squamous carcinoma, as well as to determine the correlations between clinicopathological characteristics and expression of this molecule.
Aylin Örgen Çallı +4 more
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Expression of matrix metalloproteinase-9 associated with ets-1 proto-oncogene in rat tubulointerstitial cells [PDF]
Nephrology Dialysis Transplantation, 2005 Ets-1 proto-oncogene exhibits multiple activities in the transcriptional regulation of numerous genes including metalloproteinase (MMP)-1, -3 and -9. MMPs play an important role in the remodelling of extracellular matrix in various renal diseases. However, the role of the Ets-1-MMP axis in advanced renal diseases is uncertain.
Takashi Naito +6 more
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The c-ets-1 proto-oncogenes in Xenopus laevis: expression during oogenesis and embryogenesis
Mechanisms of Development, 1993 We previously reported the cloning and sequencing of two cDNAs derived from the Xenopus laevis ets-1 gene (Stiegler et al., 1990). The Xl-ets-1a cDNA encodes a polypeptide highly homologous to known ets-1 proteins. The 3'-UTR contains two AATAAA polyadenylation signals together with three copies of the TTTTTAT sequence thought to confer a maturation ...
Patrick Stiegler +7 more
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The Journal of Immunology, 1991 Abstract Recent studies have demonstrated that the nuclear protein, Ets-1, which is preferentially expressed in lymphocytes, binds to the long terminal repeat of Moloney murine sarcoma virus and HTLV-1 and regulates gene expression. The association of Ets-1 with DNA has been shown to be lost when the protein is phosphorylated.
Cynthia L. Fisher +2 more
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Environmental Toxicology, 2023
Recent studies have shown that Solute Carrier Family 9 Member A2 (SLC9A2) could serve as a biomarker for cancer. However, its mechanism of action in osteosarcoma (OS) was still unclear.
Jiangbo Han +6 more
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Recent studies have shown that Solute Carrier Family 9 Member A2 (SLC9A2) could serve as a biomarker for cancer. However, its mechanism of action in osteosarcoma (OS) was still unclear.
Jiangbo Han +6 more
semanticscholar +1 more source
Expression of the ets-1 proto-oncogene in human pancreatic carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1998 The proto-oncogene, ets-1, is a transcription factor that controls the expression of a number of genes involved in extracellular matrix remodeling. It might play a role in cell migration and tumor invasion. To elucidate the involvement of Ets-1 in human pancreatic carcinoma, we performed immunohistochemical analysis on tissue from 10 normal pancreases ...
Tetsuya Ito +5 more
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Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis.
Oncogene, 1994 ets-1 and ets-2 genes have previously been identified by their sequence homology to the v-ets oncogene of the avian erythroblastosis virus, E26. These cellular genes have been shown to function as transcription factors important in lymphoid differentiation and activation and cellular proliferation.
Ιωάννα Μαρουλάκου +2 more
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Expression of the ets-1 proto-oncogene in human thyroid tumor.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1999 The proto-oncogene ets-1 is a transcription factor known to control the expression of a number of genes involved in extracellular matrix remodeling. To elucidate the involvement of ets-1 in human thyroid carcinoma, we examined 68 cases of thyroid carcinoma and 38 cases of benign tumors by immunohistochemical means.
Toshiyuki Nakayama +5 more
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