Results 91 to 100 of about 11,020,597 (230)

Defining acceptance criteria for silver nanoparticles: correlating synthesis quality with biological outcomes in an In Vitro Lung Cancer Model

Nano Trends
Lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the need for innovative therapeutic strategies. This study explores the development and evaluation of silver nanoparticles (AgNPs) synthesized under optimized heating
Bárbara Gomes, Marjorie Dardis Murucci, Wanderson de Souza, Beatriz Kopke Dal-Cheri, Ana Resende, Natália Yoshihara, Luths Geaquinto, José Mauro Granjeiro, Celso Sant'Anna, Leonardo Boldrini   +9 more
doaj  

Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]

, 2013
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska, AE Topolska, B Lige, B Shen, BF Kafsack, BJ Luft, C Lord, CA Hunter, Chetan E. Chitnis, Christian Slomianny, CY He, D Richard, DL Alexander, F Parussini, H El Hajj, HC Hoppe, HC Hoppe, I Mellman, J Schrevel, JB Dacks, JC Boothroyd, JE Rothman, JF Dubremetz, JM Harper, K Kremer, K Miranda, KA Joiner, KA Joiner, KM Hager, L Pelletier, L Sheiner, LH Bannister, LH Bannister, LM Kats, M Elias, M Tufet-Bayona, M Yang, Markus Meissner, ME Francia, MH Ngo, MH Ngo, MK Shaw, MS Breinich, MS Marks, NA Counihan, PJ Bradley, PJ Sloves, S Mogelsvang, SD Brydges, Stanislas Tomavo, VB Carruthers, Vern B. Carruthers, WM Henne, X Que, Z Dou   +54 more
core   +2 more sources

Economy of Operon Formation: Cotranscription Minimizes Shortfall in Protein Complexes

mBio, 2010
Genes of prokaryotes and Archaea are often organized in cotranscribed groups, or operons. In contrast, eukaryotic genes are generally transcribed independently.
Kim Sneppen, Steen Pedersen, Sandeep Krishna, Ian Dodd, Szabolcs Semsey   +4 more
doaj   +1 more source

Bacteriophage Interactions With Epithelial Cells: Therapeutic Implications

Frontiers in Microbiology, 2021
Andrzej Górski, Andrzej Górski, Andrzej Górski, Jan Borysowski, Ryszard Miȩdzybrodzki, Ryszard Miȩdzybrodzki, Ryszard Miȩdzybrodzki   +6 more
doaj   +1 more source

Stably Integrated for Assessment of Invasion Kinetics

Molecular Imaging, 2008
Salmonella Typhimurium is a common cause of gastroenteritis in humans and also localizes to neoplastic tumors in animals. Invasion of specific eukaryotic cells is a key mechanism of Salmonella interactions with host tissues.
Kelly N. Flentie, Min Qi, Seth T. Gammon, Yasmin Razia, Felix Lui, Luciano Marpegan, Aashish Manglik, David Piwnica-Worms, Jeffrey S. McKinney   +8 more
doaj   +1 more source

HPMA and HEMA copolymer bead interactions with eukaryotic cells

Materials Research, 2004
Two different hydrophilic acrylate beads were prepared via aqueous suspension polymerization. Beads produced of a hydroxypropyl methacrylate (HPMA) and ethyleneglycol methacrylate (EDMA) copolymer were obtained using a polyvinyl alcohol suspending medium.
Cristina D. Vianna-Soares, Kim Cherng-Ju, Kadriye Ciftci, Michael R. Borenstein   +3 more
doaj   +1 more source

Monitoring the reversible B to A-like transition of DNA in eukaryotic cells using Fourier transform infrared spectroscopy

Nucleic Acids Research, 2011
The ability to detect DNA conformation in eukaryotic cells is of paramount importance in understanding how some cells retain functionality in response to environmental stress.
D. Whelan, K. Bambery, P. Heraud, M. Tobin, M. Diem, D. McNaughton, B. Wood   +6 more
semanticscholar   +1 more source

A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector

Cell Reports, 2019
Summary: Many bacteria interact with target organisms using syringe-like structures called contractile injection systems (CISs). CISs structurally resemble headless bacteriophages and share evolutionarily related proteins such as the tail tube, sheath ...
Iara Rocchi, Charles F. Ericson, Kyle E. Malter, Sahar Zargar, Fabian Eisenstein, Martin Pilhofer, Sinem Beyhan, Nicholas J. Shikuma   +7 more
doaj  

Modification of bacterial effector proteins inside eukaryotic host cells

Frontiers in Cellular and Infection Microbiology, 2016
Pathogenic bacteria manipulate their hosts by delivering a number of virulence proteins -called effectors- directly into the plant or animal cells. Recent findings have shown that such effectors can suffer covalent modifications inside the eukaryotic ...
Crina Mihaela Popa, Crina Mihaela Popa, Mitsuaki Tabuchi, Marc Valls, Marc Valls   +4 more
doaj   +1 more source

Uncharged tRNA Activates GCN2 by Displacing the Protein Kinase Moiety from a Bipartite tRNA-Binding Domain [PDF]

, 2000
Protein kinase GCN2 regulates translation in amino acid–starved cells by phosphorylating eIF2. GCN2 contains a regulatory domain related to histidyl-tRNA synthetase (HisRS) postulated to bind multiple deacylated tRNAs as a general sensor of starvation ...
Anderson, James T., Dong, Jinsheng, Garcia-Barrio, Minerva, Hinnebusch, Alan G., Qiu, Hongfang   +4 more
core   +1 more source