Results 31 to 40 of about 11,020,597 (230)

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast [PDF]

open access: yes, 2012
The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as ...
Allshire, Robin C   +11 more
core   +2 more sources

The landscape of transcription errors in eukaryotic cells

open access: yesScience Advances, 2017
This paper provides the first comprehensive analysis of the fidelity of transcription in eukaryotic cells. Accurate transcription is required for the faithful expression of genetic information.
Jean-François Gout   +12 more
semanticscholar   +1 more source

Ras inhibitors gate chemoattractant concentration range for chemotaxis through controlling GPCR-mediated adaptation and cell sensitivity

open access: yesFrontiers in Immunology, 2022
Chemotaxis plays an essential role in recruitment of leukocytes to sites of inflammation. Eukaryotic cells sense chemoattractant with G protein-coupled receptors (GPCRs) and chemotax toward gradients with an enormous concentration range through ...
Xuehua Xu, Tian Jin
doaj   +1 more source

Molecular roles and function of circular RNAs in eukaryotic cells

open access: yesCellular and Molecular Life Sciences, 2017
Protein-coding and noncoding genes in eukaryotes are typically expressed as linear messenger RNAs, with exons arranged colinearly to their genomic order.
L. Holdt   +2 more
semanticscholar   +1 more source

Specific isoforms of translation initiation factor 4GI show differences in translational activity [PDF]

open access: yes, 2006
The eukaryotic initiation factor (eIF) 4GI gene locus (eIF4GI) contains three identified promoters, generating alternately spliced mRNAs, yielding a total of five eIF4GI protein isoforms.
Coldwell, Mark J, Morley, Simon J
core   +2 more sources

SF3b4: A Versatile Player in Eukaryotic Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
Spliceosomes are large protein-RNA complexes regulating pre-mRNA processing in eukaryotes. SF3b4 encodes a core subunit of the U2-type spliceosome, loss- or gain-of-function of which often associates with abnormal cell growth, leading to tumorigenesis ...
Feng Xiong, Sha Li, Sha Li
doaj   +1 more source

Bacteriophages as Potential Clinical Immune Modulators

open access: yesMicroorganisms, 2023
Bacteriophages (phages for short) are bacteria-specific viruses that have been drawing attention when it comes to countering the ever-growing antibiotic bacterial resistance, and are being seen as one of the most promising technologies against multi ...
Estêvão Brasiliense de Souza   +2 more
doaj   +1 more source

The Initiation of Eukaryotic DNA Replication.

open access: yesAnnual Review of Biochemistry, 2022
DNA replication in eukaryotic cells initiates from large numbers of sites called replication origins. Initiation of replication from these origins must be tightly controlled to ensure the entire genome is precisely duplicated in each cell cycle.
Alessandro Costa, J. Diffley
semanticscholar   +1 more source

Integrating Horizontal Gene Transfer and Common Descent to Depict Evolution and Contrast It with ‘‘Common Design [PDF]

open access: yes, 2010
Horizontal gene transfer (HGT) and common descent interact in space and time. Because events of HGT co-occur with phylogenetic evolution, it is difficult to depict evolutionary patterns graphically. Tree-like representations of life’s diversification are
Espinosa, Avelina   +1 more
core   +2 more sources

Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia

open access: yesTechnology in Cancer Research & Treatment, 2020
Objective: This study aimed to explore whether eukaryotic translation elongation factor 1 alpha 2 affected cell proliferation, migration, and apoptosis via regulating the dimethylation of eukaryotic translation elongation factor 1 alpha at lysine 55 in ...
Shan Xiao MM   +6 more
doaj   +1 more source

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