Results 51 to 60 of about 5,903,550 (301)

Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia

Technology in Cancer Research & Treatment, 2020
Objective: This study aimed to explore whether eukaryotic translation elongation factor 1 alpha 2 affected cell proliferation, migration, and apoptosis via regulating the dimethylation of eukaryotic translation elongation factor 1 alpha at lysine 55 in ...
Shan Xiao MM, Yanping Wang MM, Yuwen Ma MM, Jue Liu MD, Can’e Tang MD, Aiping Deng MB, Chunxiang Fang MB   +6 more
doaj   +1 more source

Biomembranal Myristoyl-Phosphatidylcholine as a Potential Target of the Cell Injury Activity of Vitamin D Decomposition Products in Eukaryotic Cells

Frontiers in Bioscience-Landmark
Background: Vitamin D decomposition products target a myristic acid sidechain of the predominant glycerophospholipid constructed in the biomembranes of Helicobacter pylori, causing gastric cancer in humans, and disrupt the membrane ...
Hirofumi Shimomura, Kiyofumi Wanibuchi, Kouich Hosoda, Avarzed Amgalanbaatar, Mitsuru Shoji, Shunji Hayashi   +5 more
doaj   +1 more source

A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

Nature Communications, 2023
Bacteria can affect cellular processes in other bacteria and in eukaryotic cells by injecting effectors using a type VI secretion system (T6SS). Here, Sá-Pessoa et al.
Joana Sá-Pessoa, Sara López-Montesino, Kornelia Przybyszewska, Isabel Rodríguez-Escudero, Helina Marshall, Adelia Ova, Gunnar N. Schroeder, Peter Barabas, María Molina, Tim Curtis, Víctor J. Cid, José A. Bengoechea   +11 more
doaj   +1 more source

Redox compartmentalization in eukaryotic cells [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2008
Diverse functions of eukaryotic cells are optimized by organization of compatible chemistries into distinct compartments defined by the structures of lipid-containing membranes, multiprotein complexes and oligomeric structures of saccharides and nucleic acids.
Young-Mi, Go, Dean P, Jones
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The landscape of transcription errors in eukaryotic cells

, 2017
This paper provides the first comprehensive analysis of the fidelity of transcription in eukaryotic cells.
Clark Fritsch, Marc Vermulst, Annie Li, Hossein Fazelinia, Weiyi Li, Zach Smith, Larry Singh, Michael Lynch, Steven Seeholzer, Jean-Francois Gout, Ding Hua, Kelley Thomas, Suraiya Haroon   +12 more
core   +1 more source

Interaction of bacterial extracellular microvesicles with eukaryotic cells.

Медицинская иммунология, 2021
Bacterial extracellular microvesicles (BMV) are formed by nonpathogenic, pathogenic and opportunistic bacteria. BMV are spherical bilayer-membrane organelles containing different cargoes: lipopolysaccharides, pathogen associated molecular patterns (PUMP),
D. S. Shlykova, V. M. Pisarev, A. M. Gaponov, A. V. Tutelyan   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Groups without cultured representatives dominate eukaryotic picophytoplankton in the oligotrophic South East Pacific Ocean [PDF]

, 2009
Background: Photosynthetic picoeukaryotes (PPE) with a cell size less than 3 µm play a critical role in oceanic primary production. In recent years, the composition of marine picoeukaryote communities has been intensively investigated by molecular ...
Marie, D., Vaulot, Daniel, Jardillier, Ludwig, Marie, Dominique, Xiao Li Shi, Dominique Marie, Shi, Xiao Li, Scanlan, David J., Marie Dominique, Jardillier Ludwig, Scanlan David J., Shi Xiao Li, Vaulot Daniel, David J Scanlan, Daniel Vaulot, Ludwig Jardillier   +15 more
core   +2 more sources