Results 61 to 70 of about 606,087 (302)
Phagocytosis-like cell engulfment by a planctomycete bacterium
Nature Communications, 2019 Phagocytosis is a typically eukaryotic feature that could be behind the origin of eukaryotic cells. Here, the authors describe a bacterium that can engulf other bacteria and small eukaryotic cells through a phagocytosis-like mechanism.
Takashi Shiratori +3 more
doaj +1 more source
A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector
Cell Reports, 2019 Summary: Many bacteria interact with target organisms using syringe-like structures called contractile injection systems (CISs). CISs structurally resemble headless bacteriophages and share evolutionarily related proteins such as the tail tube, sheath ...
Iara Rocchi +7 more
doaj +1 more source
Evolution: functional evolution of nuclear structure. [PDF]
, 2011 The evolution of the nucleus, the defining feature of eukaryotic cells, was long shrouded in speculation and mystery. There is now strong evidence that nuclear pore complexes (NPCs) and nuclear membranes coevolved with the endomembrane system, and that ...
Dawson, Scott C, Wilson, Katherine L
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Bottom-up assembly of functional intracellular synthetic organelles by droplet-based microfluidics
, 2020 Bottom-up synthetic biology has directed most efforts toward the construction of artificial compartmentalized systems that recreate living cell functions in their mechanical, morphological, or metabolic characteristics.
Platzman, I. +3 more
core +1 more source
A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells. [PDF]
, 2014 Dynamic instability, polarity, and spatiotemporal organization are hallmarks of the microtubule cytoskeleton that allow formation of complex structures such as the eukaryotic spindle. No similar structure has been identified in prokaryotes.
Agard, David A +6 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Bacterial toxin effector membrane targeting: Outside in, then back again.
Frontiers in Cellular and Infection Microbiology, 2012 Pathogenic bacteria utilize multiple approaches to mediate their toxicity to eukaryotic cells. Dedicated protein machines deposit toxic effectors directly inside the host, whereas secreted toxins must enter cells independently of other bacterial ...
Brett eGeissler
doaj +1 more source
A latent ability to persist: differentiation in Toxoplasma gondii [PDF]
, 2018 A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Selection of resistance to cisplatin in saccharomyces cerevisiae as a model for antineoplastic drugs studies [PDF]
, 2019 The budding yeast (S. cerevisiae) is an excellent eukaryotic model to study the antineoplastic drugs effects, due to the well-characterized metabolic and genetic characteristics and the conserved similarity in molecular mechanisms with other species ...
Burgos-Molina, Antonio Manuel +3 more
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