Results 41 to 50 of about 11,020,597 (230)

Functional capacity of Shiga-toxin promoter sequences in eukaryotic cells. [PDF]

open access: yesPLoS ONE, 2013
Shiga toxins (Stx) are the main virulence factors in enterohemorrhagic Escherichia coli (EHEC) infections, causing diarrhea and hemolytic uremic syndrome (HUS). The genes encoding for Shiga toxin-2 (Stx2) are located in a bacteriophage.
Leticia V Bentancor   +9 more
doaj   +1 more source

A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

open access: yesNature Communications, 2023
Bacteria can affect cellular processes in other bacteria and in eukaryotic cells by injecting effectors using a type VI secretion system (T6SS). Here, Sá-Pessoa et al.
Joana Sá-Pessoa   +11 more
doaj   +1 more source

Wholly Rickettsia! Reconstructed Metabolic Profile of the Quintessential Bacterial Parasite of Eukaryotic Cells

open access: yesmBio, 2017
Reductive genome evolution has purged many metabolic pathways from obligate intracellular Rickettsia (Alphaproteobacteria; Rickettsiaceae). While some aspects of host-dependent rickettsial metabolism have been characterized, the array of host-acquired ...
Timothy P. Driscoll   +8 more
semanticscholar   +1 more source

Translation inhibition by rocaglates is independent of eIF4E phosphorylation status [PDF]

open access: yes, 2016
Rocaglates are natural products that inhibit protein synthesis in eukaryotes and exhibit antineoplastic activity. In vitro biochemical assays, affinity chromatography experiments coupled with mass spectrometry analysis, and in vivo genetic screens have ...
Cencic, Regina   +4 more
core   +1 more source

Interaction of bacterial extracellular microvesicles with eukaryotic cells.

open access: yesМедицинская иммунология, 2021
Bacterial extracellular microvesicles (BMV) are formed by nonpathogenic, pathogenic and opportunistic bacteria. BMV are spherical bilayer-membrane organelles containing different cargoes: lipopolysaccharides, pathogen associated molecular patterns (PUMP),
D. S. Shlykova   +3 more
doaj   +1 more source

Phosphatidylethanolamine Is a Key Regulator of Membrane Fluidity in Eukaryotic Cells*

open access: yesJournal of Biological Chemistry, 2015
Adequate membrane fluidity is required for a variety of key cellular processes and in particular for proper function of membrane proteins. In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desaturation and cholesterol ...

semanticscholar   +1 more source

RNA Turnover: Unexpected Consequences of Being Tailed [PDF]

open access: yes, 2005
In eukaryotic cells, the 3′ poly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3′ end poly(A) tails in ...
Anderson, James T.
core   +2 more sources

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells.

open access: yesJournal of Visualized Experiments, 2016
Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of ...
Henrik D. Møller   +5 more
semanticscholar   +1 more source

Structural and Biochemical Features of Human Serum Albumin Essential for Eukaryotic Cell Culture

open access: yesInternational Journal of Molecular Sciences, 2021
Serum albumin physically interacts with fatty acids, small molecules, metal ions, and several other proteins. Binding with a plethora of bioactive substances makes it a critical transport molecule.
Vibhor Mishra, R. Heath
semanticscholar   +1 more source

The Unicellular State as a Point Source in a Quantum Biological System. [PDF]

open access: yes, 2016
A point source is the central and most important point or place for any group of cohering phenomena. Evolutionary development presumes that biological processes are sequentially linked, but neither directed from, nor centralized within, any specific ...
Miller, William B, Torday, John S
core   +3 more sources

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