Results 71 to 80 of about 7,034 (200)
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths.
Brittney N. Conn +7 more
doaj +1 more source
Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley +1 more source
Pressing environmental challenges require focused research on sustainable solutions in the domains of energy, water, food, land, and climate. The pigment eumelanin has recently been positioned as a promising candidate for solving issues in health ...
Noah Al-Shamery +6 more
doaj +1 more source
Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene. [PDF]
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant
Ben Dorshorst +11 more
doaj +1 more source
A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin +7 more
wiley +1 more source
Pigment‐associated cellular features, such as melanin levels and organelles, can be quantified in live cells with label‐free multimodal imaging. Quantitative phase imaging (cyan) measures cell mass, scattering (yellow) reports organelle content, including melanosomes, and absorbance imaging (magenta) captures pigment such as melanin.
Rebecca G. Zitnay +8 more
wiley +1 more source
Animal fiber is an important raw material for textiles. Dark animal fibers cannot be directly dyed by light colors, which is difficult to meet the demand for color diversity in clothing.
Jiajun Pan +3 more
doaj +1 more source
A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated significant ...
Nisma Mujahid +13 more
doaj +1 more source
Does the abiotic environment influence the distribution of flower and fruit colors?
Abstract Premise Color in flowers and fruits carries multiple functions, from attracting animal partners (pollinators, dispersers) to mitigating environmental stress (cold, drought, UV‐B). With research historically focusing on biotic interactions as selective agents, however, it remains unclear whether abiotic stressors impact flower and fruit colors ...
Agnes S. Dellinger +3 more
wiley +1 more source
Eumelanin electrodes in buffered aqueous media at different pH values
Eumelanin, a quinone-based biomacromolecule, is the most common form of the biopigment melanin in the human body. Eumelanin has attracted great interest due to its physicochemical properties, such as metal-ion chelation, free radical scavenging ...
A. Gouda, F. Soavi, C. Santato
semanticscholar +1 more source

