Results 81 to 90 of about 6,578 (220)
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar +12 more
wiley +1 more source
Setmelanotide in Bardet‐Biedl Syndrome: A Case Report
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith +2 more
wiley +1 more source
ABSTRACT The belted phenotype in cattle, a distinctive white belt across the midsection observed in breeds such as the Dutch Belted and Belted Galloway, is caused by a copy number variant (CNV) upstream of TWIST2, a gene involved in melanocyte development.
Rensco A. H. Hogers +8 more
wiley +1 more source
Functionalized melanin for enhanced energy storage in aqueous and ionic liquid electrolytes
Eumelanin is an interesting functional material for electrochemical applications due to its quinone/hydroquinone redox equilibrium. One major issue in the eumelanin film processing is the lack of solubility in polar solvents. In this study, the influence
Noah Al-Shamery +6 more
doaj +1 more source
A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated significant ...
Nisma Mujahid +13 more
doaj +1 more source
ABSTRACT Mottling is a widespread intra‐feather pattern present in many breeds of domestic chickens worldwide and inherited as an autosomal recessive trait. An amino acid substitution Arg332His in the EDNRB2 gene was previously reported as responsible for the mottling phenotype in several Japanese breeds of chickens.
Jingyi Li +10 more
wiley +1 more source
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths.
Brittney N. Conn +7 more
doaj +1 more source
Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene. [PDF]
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant
Ben Dorshorst +11 more
doaj +1 more source
Coloration serves several fitness‐related functions, including thermoregulation, immunity, social signaling, sexual selection, and predator avoidance. Consequently, color polymorphism can have a significant impact on a species’ interactions with its environment, including its relationships with predators, prey, and potential mates. The wood tiger moth (
Juan A. Galarza +9 more
wiley +1 more source
Pressing environmental challenges require focused research on sustainable solutions in the domains of energy, water, food, land, and climate. The pigment eumelanin has recently been positioned as a promising candidate for solving issues in health ...
Noah Al-Shamery +6 more
doaj +1 more source

