Results 71 to 80 of about 5,617 (213)

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi, Claudia Lasagni, Silvana Ciardo, Francesca Giusti, Albino Eccher, Caterina Longo   +5 more
wiley   +1 more source

Raman Spectroscopy Reveals the Presence of Both Eumelanin and Pheomelanin in the Skin of Lacertids

, 2018
R.M.-P. was supported by the fellowship BES-2010-038427 of the Spanish Ministerio de Educación.Melanic pigments play a key role in the coloration of animals, but the type of melanin pigment in black, brown, and blue colored scales of Squamata has not ...
Megia Palma, Rodrigo Manuel, Jorge, Alberto, Senda Reguera, Alberto Jorge, Rodrigo Megía-Palma, Reguera, Senda   +5 more
core   +1 more source

Eumelanin-like Poly(levodopa) Nanoscavengers for Inflammation Disease Therapy

In the current years, polydopamine nanoparticles (PDA NPs) have been extensively investigated as an eumelanin mimic. However, unlike natural eumelanin, PDA NPs contain no 5,6-dihydroxyindole-2-carboxylic acid (DHICA)-derived units and may be limited in ...
Jianhua Zhang (6347), Tianyou Wang (302431), Yiwen Li (354034), Lei Yang (102719), Xianheng Wang (4809822), Zhipeng Gu (6196154), Gaigai Duan (9159441)   +6 more
core   +1 more source

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

International Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar, Sunil Dogra, Surabhi Sinha, Keshavamurthy Vinay, Indrashis Podder, Anupam Das, Bhavesh Swarnkar, B. S. Chandrashekar, Hitaishi Mehta, Madhuri Agarwal, Muthu Sendhil Kumaran, Sonali Langar, Seemal R. Desai   +12 more
wiley   +1 more source

A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin

Cell Reports, 2017
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated significant ...
Nisma Mujahid, Yanke Liang, Ryo Murakami, Hwan Geun Choi, Allison S. Dobry, Jinhua Wang, Yusuke Suita, Qing Yu Weng, Jennifer Allouche, Lajos V. Kemeny, Andrea L. Hermann, Elisabeth M. Roider, Nathanael S. Gray, David E. Fisher   +13 more
doaj   +1 more source

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

Pediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith, Eric Sanfilippo, Lara Wine Lee   +2 more
wiley   +1 more source

Sustainable organic electrodes using black soldier fly-derived melanin for zinc-ion hybrid capacitors

Communications Materials
Pressing environmental challenges require focused research on sustainable solutions in the domains of energy, water, food, land, and climate. The pigment eumelanin has recently been positioned as a promising candidate for solving issues in health ...
Noah Al-Shamery, Xuefei Gong, Carsten Dosche, Adit Gupta, Matthew Wei Ming Tan, Jun Wei Phua, Pooi See Lee   +6 more
doaj   +1 more source

Environmental correlates of spatio‐temporal patterns of colour variation in a bird of prey: The common buzzard (Buteo buteo)

Ibis, Volume 168, Issue 3, Page 985-1001, July 2026.
High colour variability in animals has been associated with adaptability to environmental change. Establishing how such variability is distributed in time and space, and identifying environmental correlates, can help understand the processes driving it.
Kaspar Delhey, Elena F. Kappers, Mihai Valcu, Christiaan Both, Bart Kempenaers   +4 more
wiley   +1 more source

Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans

Frontiers in Microbiology
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths.
Brittney N. Conn, Jacob A. Lieberman, Priscilla Chatman, Kaitlyn Cotton, Martha A. Essandoh, Mohammad Ebqa’ai, Toby L. Nelson, Karen L. Wozniak   +7 more
doaj   +1 more source

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene. [PDF]

PLoS ONE, 2015
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant
Ben Dorshorst, Corneliu Henegar, Xiaoping Liao, Markus Sällman Almén, Carl-Johan Rubin, Shosuke Ito, Kazumasa Wakamatsu, Paul Stothard, Brian Van Doormaal, Graham Plastow, Gregory S Barsh, Leif Andersson   +11 more
doaj   +1 more source