Results 121 to 130 of about 19,340 (198)

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Oestrogen receptor phosphorylation profiles and in silico PAM50 subtyping reflect sexual dimorphism in breast cancer

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Breast cancer (BC) is most prevalent in females but also accounts for <1% of male cancer cases and 0.2% of male cancer‐related deaths. Distribution of histological subtypes, receptor status, and age of diagnosis varies based on sex, and a growing body of evidence supports sex‐specific molecular differences in BC.
Subarnarekha Chatterji, Aimee Diack, Marcin Szostok, Michael D Morgan, Valentina Silvestri, Laura Ottini, Cathy B Moelans, Paul J van Diest, Cigdem Selli, Andrew H Sims, Rasha Abu‐Eid, Valerie Speirs   +11 more
wiley   +1 more source

Ectonucleotidases CD39 and CD73 expression levels are independent and inverse predictors of survival in muscle‐invasive bladder cancer

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Bladder cancer is one of the leading causes of cancer‐related mortality worldwide. Long‐term survival is particularly poor in patients with muscle‐invasive bladder cancer (MIBC). Modulation of purinergic signaling through the ectonucleotidases CD39 and CD73 has emerged as a promising therapeutic strategy in cancer medicine.
Stephan Ledderose, Julia Schwenke, Lennert Eismann, Severin Rodler, Martina Rudelius, Carola Ledderose   +5 more
wiley   +1 more source

CCT7 Expression Affects the Prognosis of Lung Adenocarcinoma

Cancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background CCT7 is a chaperonin containing tailless complex polypeptide 1 subunit. The study focused on investigating its prognostic significance for lung adenocarcinoma (LUAD). Methods CCT7 expression in LUAD and matched non‐carcinoma lung samples was examined via TCGA database. Besides, we utilized the GEO database and RT‐qPCR for validating
Yue Li, Longqian Wei, Guiyu Feng, Guosheng Li, Jielin Ma, Xiang Gao, Jun Liu, Nuo Yang, Huafu Zhou   +8 more
wiley   +1 more source

Using Nuclear Genomic Data to Address Intractable Relationships and Gene Tree Discordance in an Ancient Group of Gymnosperms (Ephedra, Gnetales)

Ecology and Evolution, Volume 16, Issue 7, July 2026.
Low‐copy nuclear genes were used to address the notoriously difficult phylogeny of Ephedra. Additionally, we explored the potential effect of putative paralogy, intra‐locus recombination, and chimeric sequences on phylogenetic estimation. ABSTRACT The evolutionary history of Ephedra L.
Ruben Blokzijl, Catarina Rydin
wiley   +1 more source

A High-quality Reference Genome and Tissue Expression Atlas for the European Lobster (Homarus gammarus). [PDF]

Genome Biol Evol
Paris JR, Jenkins TL, Ferrer Obiol J, Gundappa MK, Regan T, Campbell L, Maslen GL, Alvarez-Jarreta J, Dyer S, Jeffries AR, Murray G, Farbos A, Bickley LK, Verbruggen B, Bateman KS, Daniels CL, Ellis CD, Ashton TJ, Tyler CR, Stentiford GD, Houston RD, Bean TP, van Aerle R, Macqueen DJ, Stevens JR, Santos EM.   +25 more
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

SorghumBase: a knowledgebase for sorghum genomics, phenomics, and stakeholder engagement. [PDF]

Genetics
Gladman N, Olson A, Kumari S, Wei S, Chougule K, Lu Z, Tello-Ruiz MK, Van Buren P, Kumar V, Zhang L, Olson A, Kim C, Braynen J, Hayes C, Xin Z, Klein R, Rooney W, Provart N, Pasha A, O'Meara A, Shakoor N, Michael TP, Harrison M, Ware D.   +23 more
europepmc   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration. [PDF]

Nucleic Acids Res
Madrigal P, Thanki AS, Fexova S, Yu ID, Chatzigeorgiou A, Zucchi I, Marugan Calles JC, Vilmovsky L, Khen A, Zhao L, Erdos K, Kurri SR, Selvakumar S, Kumbham U, Prakash A, Wang S, Green A, Ribas CE, Sweeney B, Alegbe T, Suveges D, Hemrom A, Gomez Gutierrez DE, Insua S, Jeffryes M, Pearce M, Basutkar P, Kaforou M, Cunnington A, Levin M, Kumari S, Ware D, Goutte-Gattat D, Röper K, Brown NH, Hu Y, Perrimon N, Papatheodorou I, Brazma A, Hermjakob H, Harrison M, Ocaña D, Ochoa D, McDonagh EM, Bateman A, Keane T, Vizcaíno JA, Ernst C.   +47 more
europepmc   +1 more source