Results 101 to 110 of about 19,340 (198)

Distinct Skin Penetration and Immune Responses to Ionic and Nanoparticulate Cobalt in Allergic Contact Dermatitis

open access: yesAllergy, EarlyView.
Cobalt chloride (CoCl2) and cobalt nanoparticles (CoNPs) induce a shared, severity‐dependent inflammatory response in cobalt‐sensitized skin characterized by activation of interferon signaling, inflammatory pathways (TNF/NF‐κβ, IL6‐STAT3), apoptosis/UPR, cell cycle programs, and glycolysis.
P. Werner   +8 more
wiley   +1 more source

Building a Portuguese coalition for biodiversity genomics

open access: yesnpj Biodiversity
The diverse physiography of the Portuguese land and marine territory, spanning from continental Europe to the Atlantic archipelagos, has made it an important repository of biodiversity throughout the Pleistocene glacial cycles, leading to a remarkable ...
João P. Marques   +62 more
doaj   +1 more source

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky   +28 more
wiley   +1 more source

Author Correction: The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics (npj Biodiversity, (2024), 3, 1, (28), 10.1038/s44185-024-00054-6)

open access: yes
Correction to: npj Biodiversityhttps://doi.org/10.1038/s44185-024-00054-6, published online 17 September 2024 In the orginial version of this Article, the wrong affiliation was given for Maria Angela Diroma. It should be Department of Biology, University of Florence, Sesto Fiorentino, Italy.
Mc Cartney, Ann M.   +199 more
openaire   +1 more source

Building a genome reference database for Bulgarian biodiversity - highlights from the GenBul project

open access: yes
With the advancement of high-throughput, cost-effective sequencing, the application of genomic approaches to biodiversity research is becoming increasingly accessible and inclusive. As the availability of a reference genomes database is indispensable for
Kamenova,Stefaniya   +15 more
core   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

open access: yesCancer Science, EarlyView.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li   +7 more
wiley   +1 more source

A comprehensive atlas of nuclear sequences of mitochondrial origin (NUMT) inserted into the pig genome

open access: yesGenetics Selection Evolution
Background The integration of nuclear mitochondrial DNA (mtDNA) into the mammalian genomes is an ongoing, yet rare evolutionary process that produces nuclear sequences of mitochondrial origin (NUMT).
Matteo Bolner   +7 more
doaj   +1 more source

The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): A hymenopteran species undergoing range expansion [PDF]

open access: yes
We present a reference genome assembly from an individual male Violet Carpenter Bee (Xylocopa violacea, Linnaeus 1758). The assembly is 1.02 gigabases in span. 48% of the assembly is scaffolded into 17 pseudo-chromosomal units.
Nash, Will J   +25 more
core   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

open access: yesClinical Genetics, EarlyView.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel   +27 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

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