Results 81 to 90 of about 19,340 (198)

ERGA-BGE genome of Stigmatoteuthis arcturi Robson, 1948: the jewelled squid [version 1; peer review: 2 approved]

Open Research Europe
The Stigmatoteuthis arcturi reference genome offers a valuable resource for understanding the evolutionary patterns of oceanic squids, who perform important ecological roles as both predators and prey in mesopelagic and deep-sea environments, while their
Jèssica Gómez-Garrido, Fernando Cruz, Fergal Martin, Leanne Haggerty, Tom Brown, Ainhoa Bernal-Bajo, Fernando Ángel Fernández-Álvarez, María Conejero, Nuria Escudero, Rosa Fernández, Ana Riesgo, Astrid Böhne, Rita Monteiro, Marta Gut, Laura Aguilera, Francisco Câmara Ferreira, Tyler S Alioto   +16 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

ERGA-BGE reference genome of Holothuria (Platyperona) sanctori: a sea cucumber from the Mediterranean Sea [version 2; peer review: 2 approved]

Open Research Europe
Holothuria sanctori is a common species of sea cucumber found in the Mediterranean Sea and the Northeast Atlantic Ocean. It typically inhabits shallow rocky and sandy seabeds, where it plays a key ecological role as a sediment engineer processing organic
Pedro H Oliveira, Patrick Wincker, Corinne Cruaud, Alice Moussy, Lola Demirdjian, Karine Labadie, Nuria Escudero, Thanos Dailianis, Katerina Vasileiadou, Emmanouela Vernadou, Astrid Böhne, Jean-Marc Aury, Chiara Bortoluzzi, Grigorios Skouradakis, Rosa Fernández, Danae Karakasi, Rita Monteiro, Adama Ndar, Tereza Manousaki   +18 more
doaj   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

ERGA-BGE reference genome of the forest-restricted Cretan subspecies of Hanak's bat (Pipistrellus hanaki creticus), an IUCN Vulnerable species [version 3; peer review: 2 approved]

Open Research Europe
Hanak’s bat (Pipistrellus hanaki Hulva and Benda 2004) is one of the most range restricted mammals in Europe, since it occurs only in Cyrenaica, Libya, and Crete (Greece). It is currently classified as ‘Vulnerable’ on the IUCN Red List, with its foraging
Petros Lymberakis, Manos Stratakis, Fergal Martin, Leanne Haggerty, Corinne Cruaud, Alice Moussy, Lola Demirdjian, Karine Labadie, Patrick Wincker, Manolis Papadimitrakis, Panagiotis Georgakakis, Swati Sinha, Sophie Mangenot, Nikolaos Poulakakis, Pedro H. Oliveira, Nuria Escudero, Rosa Fernández, Astrid Böhne, Jean-Marc Aury, Chiara Bortoluzzi, Danae Karakasi, Eleftherios Bitzilekis, Rita Monteiro, Caroline Belser   +23 more
doaj   +1 more source

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

The Journal of Pathology, EarlyView.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup, Julian Dosch, Christopher Dietz‐Fricke, Sara Khosraviseftejani, Esther Engel, Adalbert F de Valk, Dominic Menger, Patrick Welker, Peter J Wild, Kilian B Kennel, Maja Kantlehner, Paul K Ziegler, Florian R Greten   +12 more
wiley   +1 more source

ERGA-BGE reference genome of Gambusia holbrooki, a globally invasive freshwater fish [version 2; peer review: 2 approved]

Open Research Europe
The Gambusia holbrooki (eastern mosquitofish) reference genome will offer a crucial resource for understanding the evolution and adaptation of invasive freshwater fish species. The genome of G. holbrooki was assembled into two haplotypes through a phased
Jonathan M.D. Wood, Shane McCarthy, Fergal Martin, Leanne Haggerty, Bonnie Fraser, Francesco Santi, Clelia Gasparini, Amy Denton, Swati Sinha, Rebekah A. Oomen, Thomas Marcussen, Torsten H. Struck, Astrid Böhne, Chiara Bortoluzzi, Caroline Howard, Rita Monteiro, Mark Blaxter, Kerstin Howe   +17 more
doaj   +1 more source

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

PROTEOMICS, Volume 26, Issue 7, Page 42-56, July 2026.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia, Mélina Blanco, Meritxell Jodar, Olivier Feudjio, Marjorie Leduc, Judit Castillo, Julie Cocquet, Rafael Oliva   +7 more
wiley   +1 more source

A synthetic eco‐evolutionary proposal for the conservation of wild relatives of the olive tree

PLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement Crop wild relatives (CWR) are valuable sources of genetic diversity for plant breeding. However, the identification of wild untapped genetic resources (i.e., unexploited in crops) is not always straightforward. We propose a methodology to guide the identification and conservation of these resources that integrates both genetic
Andrés Barea‐Márquez, Guillaume Besnard, Miguel González Ximénez‐Embún, Carlos García‐Verdugo, Concepción M. Diez, José Carlos Pérez‐Girón, Rafael Rubio de Casas   +6 more
wiley   +1 more source

ERGA-BGE Genome of the viperine water snake (Natrix maura): a key species for evolutionary insights of freshwater snakes [version 1; peer review: 2 approved]

Open Research Europe
The reference genome of the freshwater snake, Natrix maura, offers a crucial resource for uncovering the genetic basis of adaptability to freshwater environments, while providing insights into hybridization and gene flow within the genus Natrix.
Jèssica Gómez-Garrido, Fernando Cruz, Fergal Martin, Leanne Haggerty, Tom Brown, Swati Sinha, Daniel Fernández-Guiberteau, Salvador Carranza, Sergi Tulloch, Laura Blasón, Nuria Escudero, Rosa Fernández, Astrid Böhne, Rita Monteiro, Marta Gut, Laura Aguilera, Francisco Câmara Ferreira, Tyler S Alioto   +17 more
doaj   +1 more source