Results 71 to 80 of about 19,199 (198)

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

ERGA-BGE genome of Stigmatoteuthis arcturi Robson, 1948: the jewelled squid [version 1; peer review: 2 approved]

Open Research Europe
The Stigmatoteuthis arcturi reference genome offers a valuable resource for understanding the evolutionary patterns of oceanic squids, who perform important ecological roles as both predators and prey in mesopelagic and deep-sea environments, while their
Jèssica Gómez-Garrido, Fernando Cruz, Fergal Martin, Leanne Haggerty, Tom Brown, Ainhoa Bernal-Bajo, Fernando Ángel Fernández-Álvarez, María Conejero, Nuria Escudero, Rosa Fernández, Ana Riesgo, Astrid Böhne, Rita Monteiro, Marta Gut, Laura Aguilera, Francisco Câmara Ferreira, Tyler S Alioto   +16 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

ERGA-BGE reference genome of Holothuria (Platyperona) sanctori: a sea cucumber from the Mediterranean Sea [version 2; peer review: 2 approved]

Open Research Europe
Holothuria sanctori is a common species of sea cucumber found in the Mediterranean Sea and the Northeast Atlantic Ocean. It typically inhabits shallow rocky and sandy seabeds, where it plays a key ecological role as a sediment engineer processing organic
Pedro H Oliveira, Patrick Wincker, Corinne Cruaud, Alice Moussy, Lola Demirdjian, Karine Labadie, Nuria Escudero, Thanos Dailianis, Katerina Vasileiadou, Emmanouela Vernadou, Astrid Böhne, Jean-Marc Aury, Chiara Bortoluzzi, Grigorios Skouradakis, Rosa Fernández, Danae Karakasi, Rita Monteiro, Adama Ndar, Tereza Manousaki   +18 more
doaj   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

ERGA-BGE reference genome of the forest-restricted Cretan subspecies of Hanak's bat (Pipistrellus hanaki creticus), an IUCN Vulnerable species [version 3; peer review: 2 approved]

Open Research Europe
Hanak’s bat (Pipistrellus hanaki Hulva and Benda 2004) is one of the most range restricted mammals in Europe, since it occurs only in Cyrenaica, Libya, and Crete (Greece). It is currently classified as ‘Vulnerable’ on the IUCN Red List, with its foraging
Petros Lymberakis, Manos Stratakis, Fergal Martin, Leanne Haggerty, Corinne Cruaud, Alice Moussy, Lola Demirdjian, Karine Labadie, Patrick Wincker, Manolis Papadimitrakis, Panagiotis Georgakakis, Swati Sinha, Sophie Mangenot, Nikolaos Poulakakis, Pedro H. Oliveira, Nuria Escudero, Rosa Fernández, Astrid Böhne, Jean-Marc Aury, Chiara Bortoluzzi, Danae Karakasi, Eleftherios Bitzilekis, Rita Monteiro, Caroline Belser   +23 more
doaj   +1 more source

Functional validation of driver mutation‐specific uveal melanoma biomarkers: role of COL9A3 in cancer cell plasticity

The Journal of Pathology, EarlyView.
Abstract Uveal melanoma (UM) is a deadly ocular malignancy with well‐described genetic alterations that predict disease outcome. However, our current understanding of the biological underpinnings of high‐risk uveal melanoma progression remains relatively limited. Using RNA expression profiles from 250 patients with UM, we identified 12 novel biomarkers
QCC van den Bosch, RM Verdijk, H Fadlelseed, TPP van den Bosch, S Owens, S Kennedy, E Kilic, E Brosens   +7 more
wiley   +1 more source

A synthetic eco‐evolutionary proposal for the conservation of wild relatives of the olive tree

PLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement Crop wild relatives (CWR) are valuable sources of genetic diversity for plant breeding. However, the identification of wild untapped genetic resources (i.e., unexploited in crops) is not always straightforward. We propose a methodology to guide the identification and conservation of these resources that integrates both genetic
Andrés Barea‐Márquez, Guillaume Besnard, Miguel González Ximénez‐Embún, Carlos García‐Verdugo, Concepción M. Diez, José Carlos Pérez‐Girón, Rafael Rubio de Casas   +6 more
wiley   +1 more source

Multimodal artificial intelligence in medical biotechnology: Integrating genomics, imaging, and clinical data for precision therapeutics

Precision Medical Sciences, EarlyView.
Overview of multimodal artificial intelligence (AI) for precision therapeutics. Diverse biomedical data modalities, including multi‐omics, medical imaging, digital pathology, electronic health records, wearable‐device data, and molecular information, are integrated through multimodal AI frameworks incorporating fusion strategies, foundation models ...
Gedion Mengistu Dejen
wiley   +1 more source

ERGA-BGE Genome of the viperine water snake (Natrix maura): a key species for evolutionary insights of freshwater snakes [version 1; peer review: 2 approved]

Open Research Europe
The reference genome of the freshwater snake, Natrix maura, offers a crucial resource for uncovering the genetic basis of adaptability to freshwater environments, while providing insights into hybridization and gene flow within the genus Natrix.
Jèssica Gómez-Garrido, Fernando Cruz, Fergal Martin, Leanne Haggerty, Tom Brown, Swati Sinha, Daniel Fernández-Guiberteau, Salvador Carranza, Sergi Tulloch, Laura Blasón, Nuria Escudero, Rosa Fernández, Astrid Böhne, Rita Monteiro, Marta Gut, Laura Aguilera, Francisco Câmara Ferreira, Tyler S Alioto   +17 more
doaj   +1 more source