Results 71 to 80 of about 19,340 (198)

ERGA Pilot Project Official Guidelines

open access: yes, 2023
This is the official guidance documentation issued to support genome teams participating in the European Reference Genome Atlas' Pilot ...
Alice Mouton   +2 more
core   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

open access: yesiMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng   +20 more
wiley   +1 more source

ERGA-BGE genome of Dendarus foraminosus: an IUCN Least Concern darkling beetle endemic to Crete (Greece) [version 3; peer review: 3 approved, 1 approved with reservations]

open access: yesOpen Research Europe
Dendarus foraminosus Mulsant and Rey, 1855 is a darkling beetle in the family Tenebrionidae and one of the many Dendarus species endemic to the island of Crete. Dendarus foraminosus is a commonly found species and is widespread in the lowland and montane
Petros Lymberakis   +23 more
doaj   +1 more source

Shifting the limits in wheat research and breeding using a fully annotated reference genome [PDF]

open access: yes, 2018
Introduction: Wheat (Triticum aestivum L.) is the most widely cultivated crop on Earth, contributing about a fifth of the total calories consumed by humans.
Cory, Aron   +242 more
core   +1 more source

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

open access: yesiMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin   +21 more
wiley   +1 more source

ERGA-BGE reference genome of Holothuria (Platyperona) sanctori: a sea cucumber from the Mediterranean Sea [version 1; peer review: 2 approved]

open access: yesOpen Research Europe
Holothuria sanctori is a common species of sea cucumber found in the Mediterranean Sea and the Northeast Atlantic Ocean. It typically inhabits shallow rocky and sandy seabeds, where it plays a key ecological role as a sediment engineer processing organic
Pedro H Oliveira   +18 more
doaj   +1 more source

ERGA Pilot Project Assembly Recommendations

open access: yes, 2023
This document contains the assembly recommendations issued during the European Reference Genome Atlas' Pilot ...
Tyler Alioto   +5 more
core   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

open access: yesiMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou   +8 more
wiley   +1 more source

ERGA-BGE reference genome of Holothuria (Platyperona) sanctori: a sea cucumber from the Mediterranean Sea [version 3; peer review: 2 approved]

open access: yesOpen Research Europe
Holothuria sanctori is a common species of sea cucumber found in the Mediterranean Sea and the Northeast Atlantic Ocean. It typically inhabits shallow rocky and sandy seabeds, where it plays a key ecological role as a sediment engineer processing organic
Pedro H Oliveira   +18 more
doaj   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

open access: yesiNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang   +9 more
wiley   +1 more source

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