Christian views of euthanasia: a comparison of Russian and western perspectives [PDF]
The following research aims at unfolding an authentic Christian attitude to euthanasia by means of a comparative analysis of Christian bioethical thinking and practice in Russia and in the West.
Lastochkina, Maria
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Comparison of Indonesian and Dutch Laws on the Implementation of Euthanasia
Developments in various matters cannot be separated from the regulations attached to them, one of which is related to euthanasia. Euthanasia in general is a treatment given to a patient to end his life intentionally with the aim of escaping suffering ...
Winda Fitri +2 more
doaj +1 more source
Determinants in Opinions Regarding Euthanasia in a Sample of Portuguese Medical Doctors
Objectives: This study seeks to establish potential determinants in the opinion of Portuguese physicians on euthanasia, and to verify if a confrontation with concrete scenarios has an effect on this opinion.
Miguel Ricou +2 more
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Attitude of the Nursing and Midwifery Students of Mazandaran University of Medical Sciences towards Euthanasia [PDF]
Background: Euthanasia has been the most controversial topic for more than 3,000 years and is among important issues in medical ethics in today’s world, having something to do with the value system of human life.
Mina Malary +6 more
doaj
Evaluation of Knowledge and Attitudes toward Euthanasia between Physicians and Caregivers
Objective: This study aimed to estimate the knowledge of the legal regulation of euthanasia and painless death among terminally ill patients, their caregivers, and attending physicians.
Sukhbaatar Chuluunsukh +4 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source

