Results 71 to 80 of about 210,115 (312)

Euthanasia and the Assessment of Patients' Autonomy Rights in the Indonesian Criminal Code

open access: yesLentera Hukum, 2020
This study aims to analyze and clarify the application of criminal law principles in cases of euthanasia. The concept of euthanasia is a new thought in criminal law that arises because of humans' desire to determine life's direction.
Fanny Tanuwijaya
doaj   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

open access: yesAdvanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash   +9 more
wiley   +1 more source

Euthanasia, or Mercy Killing [PDF]

open access: yes, 2019
Sadly, there are people in very bad medical conditions who want to die. They are in pain, they are suffering, and they no longer find their quality of life to be at an acceptable level anymore. When people like this are kept alive by
Nobis, Nathan
core  

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

Medical Students’ Attitude Towards Euthanasiain Qom in 2009

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: Among the major issues facing the new world of medical ethics is euthanasia. This is because euthanasia can be related to the value of human life.
A Kachoie   +5 more
doaj  

KESESUAIAN PENERAPAN EUTHANASIA TERHADAP PASIEN KONDISI TERMINAL ATAS PERSETUJUAN KELUARGA DALAM HUKUM POSITIF INDONESIA

open access: yesIBLAM Law Review
Normatively, the act of euthanasia in Indonesia is prohibited because in the Criminal Code it’s classified as a criminal offence as it means deprivation of the patient's life.
Mochammad Alwi Fachrezi, Tomy Michael
doaj   +1 more source

Potentiating the Efficacy of mRNA Vaccines through NIR‐II Imaging‐Guided Precise Vaccination

open access: yesAdvanced Science, EarlyView.
A supramolecular strategy is utilized to integrate IR780‐C16 lipids into conventional LNPs, pioneering a novel NIR‐II‐LNPs platform that elucidates the correlations between mRNA vaccines efficacy and vaccination parameters in a non‐invasive approach.
Mengfei Li   +6 more
wiley   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

Factors associated with behavioral euthanasia in pet dogs

open access: yesFrontiers in Veterinary Science
When pet dogs demonstrate certain serious problem behaviors, this may lead owners to choose behavioral euthanasia. However, research on behavioral euthanasia of pet dogs is sparse and previously published papers have not specifically sampled owners who ...
Miranda Hitchcock   +4 more
doaj   +1 more source

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