Results 31 to 40 of about 246,024 (234)

Elusión fiscal e intercambio de información tributaria entre Estados [PDF]

open access: yes, 2008
La relevancia que en la actualidad tiene el intercambio de información tributaria entre distintos Estados hunde sus raíces en la necesidad de encontrar mecanismos útiles y eficaces que permitan combatir el fraude, la evasión e incluso la elusión fiscal ...
Martínez Giner, Luis Alfonso
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

LOS FALLOS PENALES POR INASISTENCIA ALIMENTARIA Un desfase entre la ley y la práctica judicial

open access: yesRevista IUSTA, 2016
Las decisiones judiciales producidas por los jueces acerca del delito de inasistencia alimentaria, se caracterizan por salir de los límites considerados por el legislador.
MANUEL FERNANDO MOYA VARGAS
doaj   +1 more source

Redistribution, capital income taxation and tax evasion [PDF]

open access: yes, 1996
Factor mobility and tax evasión are two phenomena that constraint the effectiveness of redistributive policies now used by the member countries of the European Union.
López García, Salvador
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Videojugadores del League of Legends : el papel de la pasión en el uso abusivo y en el rendimiento [PDF]

open access: yes, 2016
Los juegos Massively Multiplayer Online Role Playing Games (MMORPG) han suscitado preocupación por su potencial adictivo. Los Multiplayer Online Battle Arena (MOBA) son un nuevo género poco estudiado, pero que goza de gran popularidad, en el que prima el
Bertran Martí, Enric   +1 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

El malestar del ser:

open access: yesMutatis Mutandis: Revista Internacional de Filosofía, 2019
El artículo se propone leer los ensayos de Levinas: Algunas reflexiones sobre la filosofía del hitlerismo y De la evasión como dos capítulos de un mismo discurso en el cual el autor muestra cual pueden ser los peligros y los riesgos de un pensamiento ...
Matilde Orlando
doaj  

La lentitud del intersticio: evasión y temporalidad en la narrativa en español del siglo XXI

open access: yesCuadernos LIRICO
This paper analyses texts by María Sonia Cristoff, Federico Falco, Cynthia Rimsky and Remedios Zafra based on the notion of the interstice and its configuration as a device of resistance to the speed that prevails in the contemporary city.
Borja Cano Vidal
doaj   +1 more source

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