Results 101 to 110 of about 49,849 (236)

An EKF Based Generalized Estimation Approach for Evasive Targets

, 2013
A generalized approach is presented in this paper for accurately estimating the states of the targets, which can either be non-maneuvering or undergoing various maneuvers, including the most evasive ‘barrel roll maneuver'.
Padhi, R, Bhale , PG, Bhattacharya, A, Dwivedi , PN   +3 more
core   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

Advanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong, Shi Li, Chensong Huang, Xuehong Qian, Jieyu Guo, Yahao Guo, Guifang Wu, Qi Zhang, Hongfei Tan, Yu Han, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Chaojun Yan, Wenying Qin, Changchun Li, Xing‐Zhen Chen, Ying Zhao, Cefan Zhou, Jingfeng Tang   +20 more
wiley   +1 more source

Springing into action: Comparing escape responses between bipedal and quadrupedal rodents

Ecology and Evolution
Predation is a fundamental selective pressure on animal morphology, as morphology is directly linked with physical performance and evasion. Bipedal heteromyid rodents, which are characterized by unique morphological traits such as enlarged hindlimbs ...
Grace A. Freymiller, Malachi D. Whitford, Craig P. McGowan, Timothy E. Higham, Rulon W. Clark   +4 more
doaj   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Varying Speed Cooperative Differential Game Guidance Laws With Intercept Angle Constraints

International Journal of Aerospace Engineering
For intercepting modern highly maneuvering targets, considering the velocity variation of adversaries, a varying speed cooperative differential games guidance method is proposed, which can enable multiple air-to-air missiles to intercept targets at a ...
Chao Xiahou, Hao Zhou, Wanchun Chen, Liang Yang   +3 more
doaj   +1 more source

Robotic-flapper maneuvers and fruitfly turns: Studies of an aerial robot help explain rapid banked turns in the fruitfly

, 2018
International audienceWinged insects have been a rich source of inspiration for designing flying robots, but robots can also be used to test hypotheses about the mechanisms underlying the control of insect flight (1).
Ruffier, Franck
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Integrated Longitudinal and Lateral Acceleration-Based Trajectory Planning Algorithm for Emergency Collision Avoidance Maneuver in Autonomous Vehicle

IEEE Access
While autonomous driving technology has significantly enhanced the safety and convenience of driving in the automotive industry, the field of collision avoidance technology, especially in emergency situations, still requires advanced development ...
Jaeseung Yu, Junseok Shim, Kibeom Lee
doaj   +1 more source

Lateral Evasive Maneuver with Shared Control Algorithm: A Simulator Study

Sensors
Shared control algorithms have emerged as a promising approach for enabling real-time driver automated system cooperation in automated vehicles. These algorithms allow human drivers to actively participate in the driving process while receiving continuous assistance from the automated system in specific scenarios.
Joseba Sarabia, Mauricio Marcano, Sergio E. Diaz, Asier Zubizarreta, Joshué Pérez   +4 more
openaire   +5 more sources