Results 91 to 100 of about 1,001,895 (300)

Neo-Aristotelian Naturalism and the Evolutionary Objection: Rethinking the Relevance of Empirical Science [PDF]

, 2018
Neo-Aristotelian metaethical naturalism is a modern attempt at naturalizing ethics using ideas from Aristotle’s teleological metaphysics. Proponents of this view argue that moral virtue in human beings is an instance of natural goodness, a kind of ...
C Andreou, D Hirshleifer, DJ Nicholson, DM Walsh, DS Wilson, E Jablonka, E Millgram, EA Lloyd, GC Williams, J Hacker-Wright, J Odenbaugh, K Neander, K Sterelny, L Wright, M Lott, M McCloskey, M Thompson, MD Laubichler, MJ West-Eberhard, P Foot, P Huneman, P Kitcher, R Dawkins, R Hursthouse, R Thornhill, RG Millikan, RH Frank, S Oyama, S Woodcock, SB Hrdy, T Dobzhansky, U Klein, WJ Fitzpatrick   +32 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Introduction [PDF]

, 1999
This volume of twelve specially commissioned essays about species draws on the perspectives of prominent researchers from anthropology , botany, developmental psychology , the philosophy of biology and science, protozoology, and zoology .
Wilson, Robert A.
core  

The use of information theory in evolutionary biology

, 2011
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a
Adami, Adami, Adami, Adami, Adami, Adami, Ash, Atchley, Ay, Ay, Ay, Balduzzi, Balduzzi, Barrick, Basharin, Benner, Bialek, Billeter, Blount, Callahan, Carothers, Clarke, Cooper, Cover, da Silva, Darwin, Eddy, Edlund, Ewens, Federhen, Finn, Fletcher, Fletcher, Futuyma, Garcia-Horsman, Hartl, Iliopoulos, Jühling, Klyubin, Korber, Kryazhimskiy, Landauer, Lenski, Lenski, Lenski, Levy, Li, Linsker, Lungarella, Lungarella, Maynard Smith, McGill, Pauling, Polani, Queller, Rivoire, Robinson, Schneidman, Scott, Shannon, Sporns, Sporns, Taanman, Thornton, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, van der Graaff, Waddington, Wahl, Wang, Wang, Wiener, Woods, Zahedi   +79 more
core   +1 more source

As you weed, so shall you reap: on the origin of algaculture in damselfish [PDF]

, 2010
Within their territories, damselfish cultivate particular algae for consumption. A recent study in BMC Evolutionary Biology shows extensive variation among and within fish species in the composition of these algal 'gardens', varying from monocultures to ...
Aanen, D.K.
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Regional development: contribution of evolutionary biology [PDF]

This paper tries to set out a potential of application of some evolutionary biology concepts to the issue of regional development. The objective is to show that employment of these concepts or at least inspiration by them may enrich some theories of ...
Lucie Vaskova
core  

The Machine Conception of the Organism in Development and Evolution: A Critical Analysis [PDF]

, 2014
This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for ...
Nicholson, Daniel J.
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Publication bias impacts on effect size, statistical power, and magnitude (Type M) and sign (Type S) errors in ecology and evolutionary biology [PDF]

, 2023
Yefeng Yang, Alfredo Sánchez‐Tójar, Rose E. O’Dea, Daniel W. A. Noble, Julia Koricheva, Michael D. Jennions, Timothy Parker, Malgorzata Lagisz, Shinichi Nakagawa   +8 more
openalex   +1 more source