Results 121 to 130 of about 149,013 (253)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Estimation of cation-exchange capacity in routine soil testing

open access: yesAgricultural and Food Science, 1986
The efficiency of the soil testing method used in Finland for predicting the effective cation-exchange capacity was studied in a material of 430 topsoil samples.
Raina Niskanen, Antti Jaakkola
doaj  

Spatial Variability of Soil Acidity and Lime Requirements for Potato Cultivation in the Huánuco Highlands

open access: yesAgriculture
Soil acidity is a major limiting factor for potato production in Peru’s high Andean region. This study aims to predict the spatial variability of soil acidity as a fundamental tool for recommending site-specific liming treatments and to identify the ...
Kenyi Quispe   +5 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

SOME EFFECTS OF INTENSIVE IRRIGATED AGRICULTURE ON VALENTINE SOILS IN THE NEBRASKA SANDHILLS (ACIDITY)

open access: yes, 1986
Fertilization and irrigation of coarse textured soils has resulted in marked increases in soil acidity. Stable levels of organic matter seem to buffer the soil against adverse effects of acidity such as aluminum toxicity.
SPAUGH-BARBER, ELIZABETH ANNE
core   +1 more source

Acidity and buffering properties of selected soil types of the Lasy Janowskie Landscape Park [PDF]

open access: yes, 2001
The aim of this study was to analyse the acidity and buffer abilities of selected soils occurring within terrestrial (forest, arable and meadow) ecosystems, under specific form of protection within the Lasy Janowskie Landscape Park.
Smalej, M., Chodorowski, J, Debicki, R.
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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