Results 141 to 150 of about 2,324,089 (344)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Tropical and Subtropical Agroecosystems, 2011 A key indicator of soil quality as organic carbon needs to be enhanced in the highly weathered soils predominant in southeastern Nigeria through appropriate tillage-mulch practices and cropping systems.
Sunday Ewele Obalum +3 more
doaj
Effects of Heavy Applications of Lime to Soils Derived from Volcanic Ash on the Humid Hilo and Hamakua Coasts, Island of Hawaii [PDF]
, 1966 Soils derived from volcanic parent material are of considerable agricultural importance in the humid tropics. Abundant sources of lime in the form of coral stone often occur in the vicinity of these acidic soils; thus, an understanding of the effects of ...
Rixon, A.J.
core
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Fungal population and diversity in organically amended agricultural soils of Meghalaya, India [PDF]
, 2011 The effect of different organic fertilisers (farm yard manure [FYM]; vermicompost [VC]; plant compost [PC] and integrated compost [INT], i.e. a combination of FYM, VC and PC in a 1:1:1 ratio) on the population and diversity of soil fungi was investigated
Dkhar, MS, Kayang, H, Swer, H
core
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Steel Industry Slags Compared with Calcium Carbonate in Neutralizing Acid Mine Soil [PDF]
, 2005 Author Institution: Ohio State University Agricultural Technical Institute, OHOhio has substantial lands impacted by surface mining for coal and an active steel industry.
Munn, David A.
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source