Results 161 to 170 of about 76,164 (271)

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1077-1086, April 2026.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

From Classics to Nano-Excipients and Biopolymers: Pulmonary Drug Delivery Formulations. [PDF]

Pharmaceutics
Nikou M, Chountoulesi M, Pispas S, Pippa N.   +3 more
europepmc   +1 more source

Pre‐, Pro‐, Post‐, and Synbiotics for Skin Health: A Narrative Review of Cosmetic and Dermatological Applications

Dermatological Reviews, Volume 7, Issue 2, April 2026.
ABSTRACT Background Prebiotics, probiotics, postbiotics, and synbiotics have been increasingly investigated and incorporated into cosmetic formulations to preserve or restore skin health, function, and esthetics. Objective To review biotics applications in cosmetology, discussing their concepts, general characteristics, and potential benefits and ...
Guilherme Carvalho Tavares da Silva, Kátia de Pádua Silva, Ana Carolina Furian da Silva, Larissa Pavanello, Gabriela de Moraes Saqui, Andréa Fernandes Eloy Costa da França, Gislaine Ricci Leonardi, Karina Cogo‐Müller   +7 more
wiley   +1 more source

Polymers as Stabilizing Excipients for Spray-Dried Protein Formulations. [PDF]

Pharm Res
Patil CD, Huang Y, Arte KS, Kafle N, Renawala HK, Liu J, Nie H, Zhou QT, Qu LL.   +8 more
europepmc   +1 more source

Pharmacokinetic, Safety, and Immunogenicity Similarity of High‐ and Low‐Concentration Formulations of Adalimumab Biosimilar ABP 501, Adalimumab‐Atto

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
Consistent with previously demonstrated similarity of biosimilar ABP 501 (adalimumab‐atto) with adalimumab reference product, this study in healthy adults demonstrates the pharmacokinetic, safety, and immunogenicity similarity of a high‐concentration formulation (100 mg/mL) of ABP 501 with the original 50mg/mL formulation.
Vincent Chow, Muhan Zhou, Daniel T. Mytych, Alexander Colbert, Mieke Jill Miller, Iwona Wala, Ahad Sabet, Waldemar Radziszewski   +7 more
wiley   +1 more source

Severe anaphylaxis following off-label rectal use of injectable diazepam in a febrile seizure: a case report and clinical implications. [PDF]

Int J Emerg Med
Nguyen NX, Pham NT, Le HTT, Tran QV, Tran HNT, Vo TKT, Dang CTN.   +6 more
europepmc   +1 more source

Vegetal residue‐based formulation of Trichoderma ossianense, a new indigenous vineyard species adapted to alkaline pH with potential biocontrol ability against Black‐foot disease pathogens

Pest Management Science, Volume 82, Issue 4, Page 2910-2924, April 2026.
The study identifies Trichoderma ossianense, was can be isolated from grapevine roots, is capable of growing at alkaline pH and controls black‐foot pathogens, highlighting the vegetal residue‐based formulations that preserve its viability. Abstract BACKGROUND Fungi of the Trichoderma genus are used in vineyards as biological control agents mainly ...
Laura Zanfaño, Guzmán Carro‐Huerga, Álvaro Rodríguez‐González, Sara Mayo‐Prieto, Daniela Ramírez‐Lozano, Rosa E Cardoza, Santiago Gutiérrez, Pedro A Casquero   +7 more
wiley   +1 more source

Understanding the Role of Polyols and Sugars in Reducing Aggregation in IgG₂ and IgG₄ Monoclonal Antibodies During Low-pH Viral Inactivation Step. [PDF]

Pharmaceuticals (Basel)
Hong S, Peng T, Goh LYH, Chow KT, Bahl D, Tuliani V.   +5 more
europepmc   +1 more source

Nanoemulsion design of Cynara cardunculus leaves extract rich in sesquiterpene lactones

Pest Management Science, Volume 82, Issue 4, Page 4036-4050, April 2026.
This work introduces a novel formulation strategy that advances the potential of Cynara cardunculus leaf extract enriched in sesquiterpene lactones as a bioherbicide and contributes to the broader development of sustainable weed management tools based on natural products.
Daniela Rosa, Carlos Rial, Miguel Palma, Francisco J. Rodríguez‐Mejías, Rosa M. Varela, Francisco A. Macías, Maria F. Duarte   +6 more
wiley   +1 more source

The Detrimental Effects of Crystalline Excipients: How They Jeopardize the Long-Term Stability of Freeze-Dried Polypeptide Formulations. [PDF]

Pharmaceutics
Gao H, Ouyang J, Hu ZB, Fang WJ.
europepmc   +1 more source