Neuroscience ResearchDespite the crucial role of synaptic connections and neural activity in the development and organization of cortical circuits, the mechanisms underlying the formation of functional synaptic connections in the developing human cerebral cortex remain ...
Masatoshi Nishimura +7 more
doaj
Nanoscale Biodegradable Printing for Designed Tuneability of Vaccine Delivery Kinetics
Advanced Materials, EarlyView.Spatiotemporal Controlled Release Inks of Biocompatible polyEsters (SCRIBE) is a novel 2PP resin family with sub‐micron resolution and tuneable hydrolysis. SCRIBE enables direct printing of hollow microparticles with complex chemistries and geometries inaccessible to molding techniques, which are used to modulate antibody titers and class switching as ...
David J. Peeler +16 more
wiley +1 more source
A quantitative study of the actions of excitatory amino acids and antagonists in rat hippocampal slices [PDF]
, 1988 Joanna Blake +2 more
openalex +1 more source
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Neurobiology of DiseaseExcitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists
Charlene P. Poore +7 more
doaj
Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury [PDF]
, 1993 DH Smith +3 more
openalex +1 more source
The synthesis and pharmacological evaluation of quisqualic acid and some novel excitatory amino acid mimetics [PDF]
, 1992 L-Glutamic acid and L-aspartic acid are believed to be the principal initiators of excitatory synaptic neurotransmission in the mammalian central system.
Okonkwo, P. I.
core
Recent Advances in Wide‐Bandgap Perovskite Solar Cells
Advanced Materials, EarlyView.Ubiquitous defects predominately account for photo‐instability and open‐circuit voltage losses in wide‐bandgap perovskite solar cells (WBG PSCs). This review comprehensively presents the underlying impact mechanisms, summarizes the advanced optimization strategies across various functional layers and their interfaces to develop efficient and stable WBG
Jianjun Mei, Feng Yan
wiley +1 more source
Administration of Excitatory Amino Acid Antagonists via Microdialysis Attenuates the Increase in Glucose Utilization Seen following Concussive Brain Injury [PDF]
, 1992 Tatsuro Kawamata +4 more
openalex +1 more source