Robust serotonin activation of the kisspeptin GnRH pulse generator in male and female mice.
Morris PG +7 more
europepmc +1 more source
Cancer Neuroscience: Linking Neuronal Plasticity with Brain Tumor Growth and Resistance. [PDF]
Khafaga DSR +7 more
europepmc +1 more source
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan +10 more
wiley +1 more source
Memantine as an Adjunctive Treatment for Residual Anxiety and Agitation in Early Parkinson's Disease With Depression: A Case Report. [PDF]
Haga T +6 more
europepmc +1 more source
We present the MyoRobot 3.0, an advanced platform that combines high‐resolution imaging with automated mechanical testing to improve the accuracy of single muscle fibre analysis. The system tracks fibre diameter changes during stretch, preventing major stress miscalculations.
Michael Haug +5 more
wiley +1 more source
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Galanin Receptors in the Central Nervous System: Exploring Ligand Interactions, Signal Transduction, and Potential Clinical Implications. [PDF]
Owczarek A, Blecharz-Klin K.
europepmc +1 more source
SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo +14 more
wiley +1 more source
Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area. [PDF]
Beheshti S +4 more
europepmc +1 more source

