P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C-Neuroligin 3 Mouse Model of Autism Spectrum Disorder. [PDF]
Meringolo M +12 more
europepmc +1 more source
Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits [PDF]
Karen A. Bell +3 more
openalex +1 more source
Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu +3 more
wiley +1 more source
Modeling neuron-astrocyte interactions in neural networks using distributed simulation. [PDF]
Jiang HJ +9 more
europepmc +1 more source
For the advancement of neuromorphic computing and bio‐integrated electronics, a dual‐stacked ITO/IGZO/ZrO2/Ti resistive random access memory (RRAM) device with oxygen vacancy engineering is demonstrated for reliable synaptic and nociceptive behavior. Gradual potentiation and depression, along with biologically inspired spike‐timing‐dependent plasticity
Seo‐Young Jo +4 more
wiley +1 more source
Agmatine decreases long-term potentiation <i>via</i> α2-adrenergic receptor and imidazoline type 1 receptor in the hippocampus. [PDF]
Chang W, An J, Jang SH, Kim M, Min SS.
europepmc +1 more source
MXene‐Based Flexible Memory and Neuromorphic Devices
The unique two‐dimensional structure, excellent electrical conductivity, and diverse surface groups of MXenes have garnered significant attention. Coupled with their exceptional flexibility, MXene‐based devices hold immense potential for flexible memory and neuromorphic systems. This review comprehensively discusses the fundamentals of flexible devices,
Yan Li +13 more
wiley +1 more source
Playing Multiple Parts: Unique Enzymatic and Structural Roles Orchestrated by SYNGAP1. [PDF]
Buchanan GF.
europepmc +1 more source

