Recording of excitatory postsynaptic potentials after tonic stimulation from hybrid neural circuit
, 2018 Albina Lebedeva
openalex +2 more sources
Rare dysfunctional SCN2A variants are associated with malformation of cortical development
Epilepsia, Volume 66, Issue 3, Page 914-928, March 2025.Abstract Objective SCN2A encodes the voltage‐gated sodium (Na+) channel α subunit NaV1.2, which is important for the generation and forward and back propagation of action potentials in neurons. Genetic variants in SCN2A are associated with a spectrum of neurodevelopmental disorders.
Jérôme Clatot +19 more
wiley +1 more source
Precise rewiring of corticospinal axons and spinal interneurons via near-infrared optogenetics for spinal cord injury treatment. [PDF]
Sci AdvJi Z +7 more
europepmc +1 more source
Preferential superficial cortical layer activation during seizure propagation
Epilepsia, Volume 66, Issue 3, Page 929-941, March 2025.Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya +4 more
wiley +1 more source
Chronic reduction of synaptic proteins in the epileptogenic lesion of patients with hippocampal sclerosis. [PDF]
Front Mol NeurosciOota-Ishigaki A +7 more
europepmc +1 more source
Fast activity chirp patterns in focal seizures from patients and animal models
Epilepsia, Volume 66, Issue 3, Page 621-631, March 2025.Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque +6 more
wiley +1 more source
Spike Timing-Dependent Plasticity at Layer 2/3 Horizontal Connections Between Neighboring Columns During Synapse Formation Before the Critical Period in the Developing Barrel Cortex. [PDF]
CellsItami C, Kimura F.
europepmc +1 more source
Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity
Epilepsia, EarlyView.Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang +8 more
wiley +1 more source