Results 31 to 40 of about 179,338 (253)
Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
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Molecular Autism, 2020 Background DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules.
Taesun Yoo +5 more
doaj +1 more source
Synaptic potentiation of dual‐component excitatory postsynaptic currents in the rat hippocampus. [PDF]
The Journal of Physiology, 1995 1. Whole‐cell patch‐clamp recording has been used to study tetanus‐induced synaptic potentiation of dual‐component excitatory postsynaptic currents (EPSCs) in the CA1 region of rat hippocampal slices, following blockade of GABAA and GABAB receptor‐mediated synaptic inhibition. 2.
K. A. Clark, G. Collingridge
semanticscholar +3 more sources
Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma
Neurobiology of Disease, 2016 Lesioned neuronal circuits form new functional connections after a traumatic brain injury (TBI). In humans and animal models, aberrant excitatory connections that form after TBI may contribute to the pathogenesis of post-traumatic epilepsy.
D. Koji Takahashi +4 more
doaj +1 more source
Long-Tailed Characteristics of Neural Activity Induced by Structural Network Properties
Frontiers in Applied Mathematics and Statistics, 2022 Over the past few decades, neuroscience studies have elucidated the structural/anatomical network characteristics in the brain and their associations with functional networks and the dynamics of neural activity.
Sou Nobukawa, Sou Nobukawa
doaj +1 more source
Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia [PDF]
, 1999 Little is known about the nature of the calcium channels controlling neurotransmitter release from preganglionic parasympathetic nerve fibres. In the present study, the effects of selective calcium channel antagonists and amiloride were investigated on ...
A.B Smith +33 more
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Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus
Molecular Brain, 2020 The receptor deleted in colorectal cancer (DCC) and its ligand netrin-1 are essential for axon guidance during development and are expressed by neurons in the mature brain.
Stephen D. Glasgow +6 more
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BMC Neuroscience, 2023 Background The release of various neurotransmitters and thereby the excitability of neuronal circuits are regulated by the endocannabinoid system in an activity-dependent manner. Hippocampal long-term potentiation (LTP) is augmented in cannabinoid type 1
Masoumeh Nazari +4 more
doaj +1 more source
Functional maps of neocortical local circuitry
Frontiers in Neuroscience, 2007 This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
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Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]
, 2014 Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J +2 more
core +1 more source