Functional maps of neocortical local circuitry
This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
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Neuromodulation of Chemical Synaptic Transmission Driven by THz Photons
Postsynaptic currents of chemical synapse are modulated by multitudinous neurotransmitters, such as acetylcholine, dopamine, glutamate, and γ-aminobutyric acid, many of which have been used in the treatment of neurological diseases.
Xiaoxuan Tan+3 more
doaj +1 more source
Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus
Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj
Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits ...
Hui Ye, Stephanie Kaszuba
doaj +1 more source
Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia [PDF]
Little is known about the nature of the calcium channels controlling neurotransmitter release from preganglionic parasympathetic nerve fibres. In the present study, the effects of selective calcium channel antagonists and amiloride were investigated on ...
A.B Smith+33 more
core +1 more source
The Mammalian Interaural Time Difference Detection Circuit Is Differentially Controlled by GABAB Receptors during Development [PDF]
Throughout development GABAB receptors (GABABRs) are widely expressed in the mammalian brain. In mature auditory brainstem neurons, GABABRs are involved in the short-term regulation of the strength and dynamics of excitatory and inhibitory inputs, thus ...
Grothe, Benedikt+2 more
core +1 more source
Information processing occurs via critical avalanches in a model of the primary visual cortex [PDF]
We study a new biologically motivated model for the Macaque monkey primary visual cortex which presents power-law avalanches after a visual stimulus. The signal propagates through all the layers of the model via avalanches that depend on network structure and synaptic parameter.
arxiv +1 more source
Synaptic potentiation of dual‐component excitatory postsynaptic currents in the rat hippocampus. [PDF]
1. Whole‐cell patch‐clamp recording has been used to study tetanus‐induced synaptic potentiation of dual‐component excitatory postsynaptic currents (EPSCs) in the CA1 region of rat hippocampal slices, following blockade of GABAA and GABAB receptor‐mediated synaptic inhibition. 2.
K A Clark, Graham L. Collingridge
openaire +3 more sources
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]
1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
Hablitz, John H., Sutor, Bernd
core +1 more source
A minimal model for synaptic integration in simple neurons [PDF]
Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of excitatory inputs from synapses and illustrate its use by characterizing some functional properties of postsynaptic ...
arxiv +1 more source