Results 51 to 60 of about 174,824 (351)
Neurobiology of Disease, 2013 After 1 h of lithium-pilocarpine status epilepticus (SE), immunocytochemical labeling of NMDA receptor NR1 subunits reveals relocation of subunits from the interior to the cell surface of dentate gyrus granule cells and CA3 pyramidal cells ...
David E. Naylor +3 more
doaj +1 more source
Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]
, 2019 FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran +14 more
core +1 more source
γ-Hydroxybutyrate inhibits excitatory postsynaptic potentials in rat hippocampal slices
European Journal of Pharmacology, 1999 Gamma-Hydroxybutyrate (GHB) has been shown to mimic different central actions of ethanol, to suppress alcohol withdrawal syndrome, and to reduce alcohol consumption both in rats and in humans. The aim of the present study was to determine if GHB shared with alcohol the ability to inhibit glutamate action at both NMDA and AMPA/kainate receptors.
BERTON, FULVIA +6 more
openaire +5 more sources
Supervised Associative Learning in Spiking Neural Network [PDF]
, 2005 In this paper, we propose a simple supervised associative learning approach for spiking neural networks. In an excitatory-inhibitory network paradigm with Izhikevich spiking neurons, synaptic plasticity is implemented on excitatory to excitatory synapses
F. Crick +6 more
core +1 more source
Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction. [PDF]
PLoS ONE, 2014 Members of the TGF-β superfamily play numerous roles in nervous system development and function. In Drosophila, retrograde BMP signaling at the neuromuscular junction (NMJ) is required presynaptically for proper synapse growth and neurotransmitter ...
Myung-Jun Kim, Michael B O'Connor
doaj +1 more source
Journal of Neuroscience, 1988 These experiments show that a synaptic response in brain, namely, the late inhibitory postsynaptic potential (IPSP) of hippocampal CA3 neurons in the rat hippocampal slice, was blocked by 2 compounds affecting guanosine triphosphate (GTP)-binding ...
RH Thalmann
semanticscholar +1 more source
Gain modulation of synaptic inputs by network state in auditory cortex in vivo [PDF]
, 2015 The cortical network recurrent circuitry generates spontaneous activity organized into Up (active) and Down (quiescent) states during slow-wave sleep or anesthesia.
Destexhe, Alain +4 more
core +3 more sources
Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]
, 2017 The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core +1 more source
Alterations in brain connectivity due to plasticity and synaptic delay
, 2017 Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M. +8 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source