Results 61 to 70 of about 363,862 (308)

One‐Shot Remote Integration of Macromolecular Synaptic Elements on a Chip for Ultrathin Flexible Neural Network System

Advanced Materials, EarlyView.
A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee, Jaehoon Lee, Hyeonsu Bang, Tae Woong Yoon, Jong Hwan Ko, Guobing Zhang, Ji‐Sang Park, Il Jeon, Sungjoo Lee, Boseok Kang   +9 more
wiley   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss

Frontiers in Cellular Neuroscience, 2017
The axon initial segment (AIS) is the site of action potential (AP) initiation, thus a crucial regulator of neuronal activity. In excitatory pyramidal neurons, the high density of voltage-gated sodium channels (NaV1.6) at the distal AIS regulates AP ...
Michal Vascak, Jianli Sun, Matthew Baer, Kimberle M. Jacobs, John T. Povlishock   +4 more
doaj   +1 more source

Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]

, 2019
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran, Dou, Longyu, Liang, Tiebing, Liu, Ming, Qiu, Bin, Ren, Wei, Shou, Weinian, Stewart, Robert B., Wang, Chao, Wang, Jun, Williams, Kent E., Xie, Zhongwen, Xu, Yuxue, Yong, Weidong, Zhao, Zhenwen   +14 more
core   +1 more source

Modulating Trapping in Low‐Dimensional Lead–Tin Halides for Energy‐Efficient Neuromorphic Electronics

Advanced Materials, EarlyView.
Robust 2D Ruddlesden–Popper lead‐tin perovskites demonstrate exceptional resistive switching memory performance after cesium carbonate deposition, achieving a high accuracy of 90.1% in MNIST pattern recognition. Additionally, a novel energy‐efficient content‐addressable memory architecture, based on perovskite memristive devices, is proposed for ...
Lijun Chen, Saad Saleh, Filippo Tavormina, Lorenzo Di Mario, Jiaxiong Li, Zhiqiang Xie, Norberto Masciocchi, Christoph J. Brabec, Boris Koldehofe, Maria Antonietta Loi   +9 more
wiley   +1 more source

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

Iranian Journal of Medical Sciences, 2016
Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown.
Chengdong Yuan, Yajun Zhang, Yu Zhang, Song Cao, Yuan Wang, Bao Fu, Tian Yu   +6 more
doaj  

Exercise-Induced Fatigue Impairs Bidirectional Corticostriatal Synaptic Plasticity

Frontiers in Cellular Neuroscience, 2018
Exercise-induced fatigue (EF) is a ubiquitous phenomenon in sports competition and training. It can impair athletes’ motor skill execution and cognition.
Jing Ma, Huimin Chen, Xiaoli Liu, Lingtao Zhang, Decai Qiao   +4 more
doaj   +1 more source

Tuning a binary ferromagnet into a multi-state synapse with spin-orbit torque induced plasticity [PDF]

Advanced Functional Materials, 29 (25), 1808104 (2019), 2018
Inspired by ion-dominated synaptic plasticity in human brain, artificial synapses for neuromorphic computing adopt charge-related quantities as their weights. Despite the existing charge derived synaptic emulations, schemes of controlling electron spins in ferromagnetic devices have also attracted considerable interest due to their advantages of low ...
arxiv   +1 more source

Responsive Molecules for Organic Neuromorphic Devices: Harnessing Memory Diversification

Advanced Materials, EarlyView.
Responsive molecules are essential for organic in‐sensor computing devices. This Review highlights recent advances in thedesign, synthesis, and incorporation of electrically, optically, and magnetically responsive molecules in multifunctional synaptic perception devices endowedwith both nonvolatile and volatile memory diversification. By exploiting the
Yusheng Chen, Bin Han, Marco Gobbi, Lili Hou, Paolo Samorì   +4 more
wiley   +1 more source

GABAB Receptors Augment TRPC3-Mediated Slow Excitatory Postsynaptic Current to Regulate Cerebellar Purkinje Neuron Response to Type-1 Metabotropic Glutamate Receptor Activation

Cells, 2018
During strong parallel fiber stimulation, glutamate released at parallel fiber-Purkinje cell synapses activates type-1 metabotropic glutamate receptor (mGluR1) to trigger a slow excitatory postsynaptic current (sEPSC) in cerebellar Purkinje neurons.
Jinbin Tian, Michael X. Zhu
doaj   +1 more source