Results 71 to 80 of about 179,338 (253)

The Mechanistic Basis for Successful Spinal Cord Stimulation to Generate Steady Motor Outputs

Frontiers in Cellular Neuroscience, 2019
Electrical stimulation of the spinal cord is a promising rehabilitation intervention to restore/augment motor function after spinal cord injury (SCI).
Amr A. Mahrous, Amr A. Mahrous, Mohamed H. Mousa, Sherif M. Elbasiouny, Sherif M. Elbasiouny   +4 more
doaj   +1 more source

Supervised Associative Learning in Spiking Neural Network [PDF]

, 2005
In this paper, we propose a simple supervised associative learning approach for spiking neural networks. In an excitatory-inhibitory network paradigm with Izhikevich spiking neurons, synaptic plasticity is implemented on excitatory to excitatory synapses
F. Crick, E.M. Izhikevich, E.M. Izhikevich, A. Kasinski, P. Dayan, N. Brunel, H. Paugam-Moisy   +6 more
core   +1 more source

Effect of Background Synaptic Activity on Excitatory-Postsynaptic Potential-Spike Coupling

, 2003
Veronika Zsiros
openalex   +2 more sources

Selective activation of BK channels in small-headed dendritic spines suppresses excitatory postsynaptic potentials [PDF]

, 2021
Sabrina Tazerart, Maxime G. Blanchard, Soledad Miranda‐Rottmann, Diana Mitchell, Bruno Navea Pina, Connon I. Thomas, Naomi Kamasawa, Roberto Araya   +7 more
openalex   +1 more source

Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice

Molecular Brain, 2021
The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders.
Chunmei Jin, Yeunkum Lee, Hyojin Kang, Kwon Jeong, Joori Park, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Hyunyoung Seong, Yoonhee Kim, Hosung Jung, Jin Young Kim, Yoon Ki Kim, Kihoon Han   +13 more
doaj   +1 more source

Essential Functions of the Transcription Factor Npas4 in Neural Circuit Development, Plasticity, and Diseases

Frontiers in Neuroscience, 2020
Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu, Ouyang Guo, Zhihang Zhen, Junli Zhen   +3 more
doaj   +1 more source

A framework for generalized group testing with inhibitors and its potential application in neuroscience [PDF]

, 2019
The main goal of group testing with inhibitors (GTI) is to efficiently identify a small number of defective items and inhibitor items in a large set of items.
Bui, Thach V., Cheraghchi, Mahdi, Echizen, Isao, Kuribayashi, Minoru   +3 more
core   +1 more source

Tutorial: Neuromorphic spiking neural networks for temporal learning

, 2018
Spiking neural networks (SNN) as time-dependent hypotheses consisting of spiking nodes (neurons) and directed edges (synapses) are believed to offer unique solutions to reward prediction tasks and the related feedback that are classified as reinforcement
Jeong, Doo Seok
core   +1 more source

Molecular investigation of ergot alkaloid ergotamine's modulatory effects on glycine receptors expressed in Xenopus oocytes

Computational and Structural Biotechnology Journal
The relationship between oxidative stress and glycine receptors is complex, involving multiple mechanisms through which reactive oxygen species can modify glycine receptor function. Understanding these interactions is essential for developing therapeutic
Sanung Eom, Minsu Pyeon, Myungmi Moon, Jeongyeon Yun, Jaehui Yang, Jihwon Yun, Hye Duck Yeom, Mee-Hyun Lee, Gihyun Lee, Junho H. Lee   +9 more
doaj   +1 more source

AST-120 Protects Cognitive and Emotional Impairment in Chronic Kidney Disease Induced by 5/6 Nephrectomy

Brain Sciences
Background: Uremic toxins resulting from chronic kidney disease (CKD) can cause cognitive and emotional disorders, as well as cardiovascular diseases. Indoxyl sulfate (IS) and p-cresol are notable uremic toxins found in patients with CKD.
Yeon Hee Yu, Hyuna Im, Samel Park, Beomjong Song, Dae-Kyoon Park, Duk-Soo Kim, Hyo-Wook Gil   +6 more
doaj   +1 more source