Results 71 to 80 of about 408,389 (348)

Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans [PDF]

, 2019
Mutations in pre-synaptic voltage gated calcium channels can lead to familial hemiplegic migraine type 1 (FHM1). While mammalian studies indicate that the migraine brain is hyperexcitable due to enhanced excitation or reduced inhibition, the molecular ...
Alkema, Mark J., Francis, Michael M., Gao, Shangbang, Grant, Jeff, Huang, Yung Chi, Mulcahy, Ben, Pirri, Jennifer K., Rayes, Diego Hernán, Saheki, Yasunori, Zhen, Mei   +9 more
core   +1 more source

Integration of Perovskite/Low‐Dimensional Material Heterostructures for Optoelectronics and Artificial Visual Systems

Advanced Functional Materials, EarlyView.
Heterojunctions combining halide perovskites with low‐dimensional materials enhance optoelectronic devices by enabling precise charge control and improving efficiency, stability, and speed. These synergies advance flexible electronics, wearable sensors, and neuromorphic computing, mimicking biological vision for real‐time image analysis and intelligent
Yu‐Jin Du, Junjie Yang, Ziyu Lv, Yongbiao Zhai, Zezhuang Yi, Yuhui Xie, Ming‐Lin Zheng, Xiangyu Ma, Guodong Gong, Yan Wang, Ye Zhou, Su‐Ting Han   +11 more
wiley   +1 more source

Equilibrium Properties of Temporally Asymmetric Hebbian Plasticity [PDF]

, 2000
A theory of temporally asymmetric Hebb (TAH) rules which depress or potentiate synapses depending upon whether the postsynaptic cell fires before or after the presynaptic one is presented.
C. W. Eurich, Daniel D. Lee, G. Q. Bi, H. Markram, H. Sompolinsky, Jonathan Rubin, L. F. Abbott, M. C. W. van Rossum, R. Kempter, R. P. N. Rao, W. M. Kistler   +10 more
core   +4 more sources

Mimicking synaptic plasticity with wedged Pt/Co/Pt spin-orbit torque device [PDF]

J. Phys. D: Appl. Phys. 55, 095001 (2022)
We fabricated a wedge-shaped Pt/Co/Pt device with perpendicular magnetic anisotropy and manifested that the Co magnetization can be solely switched by spin-orbit torque without any magnetic field. Similar to the synaptic weight, we observed that the state of Co magnetization (presented by the anomalous Hall resistance RH) of the wedged Pt/Co/Pt device ...
arxiv   +1 more source

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source

Data compression of excitatory postsynaptic potentials

, 2015
Reducing the size of biosignal data is important because a huge amount of data is made by various experiments. In this reported work excitatory postsynaptic potentials (EPSPs) which are one of the biosignal types are efficiently compressed.
Hyejin An, K. Cha, Se-Young Choi, Hyun-Chool Shin   +3 more
semanticscholar   +1 more source

Distinct forms of synaptic inhibition and neuromodulation regulate calretinin positive neuron excitability in the spinal cord dorsal horn [PDF]

, 2016
The dorsal horn (DH) of the spinal cord contains a heterogenous population of neurons that process incoming sensory signals before information ascends to the brain.
Boyle, K.A., Callister, R.J., Graham, B.A., Hughes, D.I., Jobling, P., Mustapa, M., Smith, K.M.   +6 more
core   +1 more source

Multi-contact synapses for stable networks: a spike-timing dependent model of dendritic spine plasticity and turnover [PDF]

Cerebral Cortex 28-4 (2018) 1396-1415, 2016
Excitatory synaptic connections in the adult neocortex consist of multiple synaptic contacts, almost exclusively formed on dendritic spines. Changes of dendritic spine shape and volume, a correlate of synaptic strength, can be tracked in vivo for weeks.
arxiv   +1 more source

One‐Shot Remote Integration of Macromolecular Synaptic Elements on a Chip for Ultrathin Flexible Neural Network System

Advanced Materials, EarlyView.
A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee, Jaehoon Lee, Hyeonsu Bang, Tae Woong Yoon, Jong Hwan Ko, Guobing Zhang, Ji‐Sang Park, Il Jeon, Sungjoo Lee, Boseok Kang   +9 more
wiley   +1 more source

Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss

Frontiers in Cellular Neuroscience, 2017
The axon initial segment (AIS) is the site of action potential (AP) initiation, thus a crucial regulator of neuronal activity. In excitatory pyramidal neurons, the high density of voltage-gated sodium channels (NaV1.6) at the distal AIS regulates AP ...
Michal Vascak, Jianli Sun, Matthew Baer, Kimberle M. Jacobs, John T. Povlishock   +4 more
doaj   +1 more source